Line-field confocal optical coherence tomography in dermato-oncology: A literature review towards harmonized histopathology-integrated terminology

Publikation: Bidrag til tidsskriftReviewForskningfagfællebedømt

Standard

Line-field confocal optical coherence tomography in dermato-oncology : A literature review towards harmonized histopathology-integrated terminology. / Jacobsen, Kevin; Ortner, Vinzent Kevin; Wenande, Emily; Sahu, Aditi; Paasch, Uwe; Haedersdal, Merete.

I: Experimental Dermatology, Bind 33, Nr. 4, e15057, 2024.

Publikation: Bidrag til tidsskriftReviewForskningfagfællebedømt

Harvard

Jacobsen, K, Ortner, VK, Wenande, E, Sahu, A, Paasch, U & Haedersdal, M 2024, 'Line-field confocal optical coherence tomography in dermato-oncology: A literature review towards harmonized histopathology-integrated terminology', Experimental Dermatology, bind 33, nr. 4, e15057. https://doi.org/10.1111/exd.15057

APA

Jacobsen, K., Ortner, V. K., Wenande, E., Sahu, A., Paasch, U., & Haedersdal, M. (2024). Line-field confocal optical coherence tomography in dermato-oncology: A literature review towards harmonized histopathology-integrated terminology. Experimental Dermatology, 33(4), [e15057]. https://doi.org/10.1111/exd.15057

Vancouver

Jacobsen K, Ortner VK, Wenande E, Sahu A, Paasch U, Haedersdal M. Line-field confocal optical coherence tomography in dermato-oncology: A literature review towards harmonized histopathology-integrated terminology. Experimental Dermatology. 2024;33(4). e15057. https://doi.org/10.1111/exd.15057

Author

Jacobsen, Kevin ; Ortner, Vinzent Kevin ; Wenande, Emily ; Sahu, Aditi ; Paasch, Uwe ; Haedersdal, Merete. / Line-field confocal optical coherence tomography in dermato-oncology : A literature review towards harmonized histopathology-integrated terminology. I: Experimental Dermatology. 2024 ; Bind 33, Nr. 4.

Bibtex

@article{24a535fa0e5144888ac66bc63f6c1a6e,
title = "Line-field confocal optical coherence tomography in dermato-oncology: A literature review towards harmonized histopathology-integrated terminology",
abstract = "Non-invasive diagnostics like line-field confocal optical coherence tomography (LC-OCT) are being implemented in dermato-oncology. However, unification of terminology in LC-OCT is lacking. By reviewing the LC-OCT literature in the field of dermato-oncology, this study aimed to develop a unified terminological glossary integrated with traditional histopathology. A PRISMA-guided literature-search was conducted for English-language publications on LC-OCT of actinic keratosis (AK), keratinocyte carcinoma (KC), and malignant melanoma (MM). Study characteristics and terminology were compiled. To harmonize LC-OCT terminology and integrate with histopathology, synonymous terms for image features of AK, KC, and MM were merged by two authors, organized by skin layer and lesion-type. A subset of key LC-OCT image-markers with histopathological correlates that in combination were typical of AK, squamous cell carcinoma in situ (SCCis), invasive squamous cell carcinoma (SCC), basal cell carcinoma (BCC), and MM in traditional histopathology, were selected from the glossary by an experienced dermatopathologist. Seventeen observational studies of AK (7 studies), KC (13 studies), MM (7 studies) utilizing LC-OCT were included, with 117 terms describing either AK, KC, or MM. These were merged to produce 45 merged-terms (61.5% reduction); 5 assigned to the stratum corneum (SC), 23 to the viable epidermis, 2 to dermo-epidermal junction (DEJ) and 15 to the dermis. For each lesion, mandatory key image-markers were a well-defined DEJ and presence of mild/moderate but not severe epidermal dysplasia for AK, severe epidermal dysplasia and well-defined DEJ for SCCis, interrupted DEJ and/or dermal broad infiltrative strands for invasive SCC, dermal lobules connected and/or unconnected to the epidermis for BCC, as well as single atypical melanocytes and/or nest of atypical melanocytes in the epidermis or dermis for MM. This review compiles evidence on LC-OCT in dermato-oncology, providing a harmonized histopathology-integrated terminology and key image-markers for each lesion. Further evaluation is required to determine the clinical value of these findings.",
keywords = "carcinoma, basal cell, carcinoma, squamous cell, keratosis, actinic, melanoma, microscopy, confocal, optical coherence, tomography, optical imaging, review, skin neoplasms",
author = "Kevin Jacobsen and Ortner, {Vinzent Kevin} and Emily Wenande and Aditi Sahu and Uwe Paasch and Merete Haedersdal",
note = "Publisher Copyright: {\textcopyright} 2024 The Authors. Experimental Dermatology published by John Wiley & Sons Ltd.",
year = "2024",
doi = "10.1111/exd.15057",
language = "English",
volume = "33",
journal = "Experimental Dermatology",
issn = "0906-6705",
publisher = "Wiley-Blackwell",
number = "4",

}

RIS

TY - JOUR

T1 - Line-field confocal optical coherence tomography in dermato-oncology

T2 - A literature review towards harmonized histopathology-integrated terminology

AU - Jacobsen, Kevin

AU - Ortner, Vinzent Kevin

AU - Wenande, Emily

AU - Sahu, Aditi

AU - Paasch, Uwe

AU - Haedersdal, Merete

N1 - Publisher Copyright: © 2024 The Authors. Experimental Dermatology published by John Wiley & Sons Ltd.

PY - 2024

Y1 - 2024

N2 - Non-invasive diagnostics like line-field confocal optical coherence tomography (LC-OCT) are being implemented in dermato-oncology. However, unification of terminology in LC-OCT is lacking. By reviewing the LC-OCT literature in the field of dermato-oncology, this study aimed to develop a unified terminological glossary integrated with traditional histopathology. A PRISMA-guided literature-search was conducted for English-language publications on LC-OCT of actinic keratosis (AK), keratinocyte carcinoma (KC), and malignant melanoma (MM). Study characteristics and terminology were compiled. To harmonize LC-OCT terminology and integrate with histopathology, synonymous terms for image features of AK, KC, and MM were merged by two authors, organized by skin layer and lesion-type. A subset of key LC-OCT image-markers with histopathological correlates that in combination were typical of AK, squamous cell carcinoma in situ (SCCis), invasive squamous cell carcinoma (SCC), basal cell carcinoma (BCC), and MM in traditional histopathology, were selected from the glossary by an experienced dermatopathologist. Seventeen observational studies of AK (7 studies), KC (13 studies), MM (7 studies) utilizing LC-OCT were included, with 117 terms describing either AK, KC, or MM. These were merged to produce 45 merged-terms (61.5% reduction); 5 assigned to the stratum corneum (SC), 23 to the viable epidermis, 2 to dermo-epidermal junction (DEJ) and 15 to the dermis. For each lesion, mandatory key image-markers were a well-defined DEJ and presence of mild/moderate but not severe epidermal dysplasia for AK, severe epidermal dysplasia and well-defined DEJ for SCCis, interrupted DEJ and/or dermal broad infiltrative strands for invasive SCC, dermal lobules connected and/or unconnected to the epidermis for BCC, as well as single atypical melanocytes and/or nest of atypical melanocytes in the epidermis or dermis for MM. This review compiles evidence on LC-OCT in dermato-oncology, providing a harmonized histopathology-integrated terminology and key image-markers for each lesion. Further evaluation is required to determine the clinical value of these findings.

AB - Non-invasive diagnostics like line-field confocal optical coherence tomography (LC-OCT) are being implemented in dermato-oncology. However, unification of terminology in LC-OCT is lacking. By reviewing the LC-OCT literature in the field of dermato-oncology, this study aimed to develop a unified terminological glossary integrated with traditional histopathology. A PRISMA-guided literature-search was conducted for English-language publications on LC-OCT of actinic keratosis (AK), keratinocyte carcinoma (KC), and malignant melanoma (MM). Study characteristics and terminology were compiled. To harmonize LC-OCT terminology and integrate with histopathology, synonymous terms for image features of AK, KC, and MM were merged by two authors, organized by skin layer and lesion-type. A subset of key LC-OCT image-markers with histopathological correlates that in combination were typical of AK, squamous cell carcinoma in situ (SCCis), invasive squamous cell carcinoma (SCC), basal cell carcinoma (BCC), and MM in traditional histopathology, were selected from the glossary by an experienced dermatopathologist. Seventeen observational studies of AK (7 studies), KC (13 studies), MM (7 studies) utilizing LC-OCT were included, with 117 terms describing either AK, KC, or MM. These were merged to produce 45 merged-terms (61.5% reduction); 5 assigned to the stratum corneum (SC), 23 to the viable epidermis, 2 to dermo-epidermal junction (DEJ) and 15 to the dermis. For each lesion, mandatory key image-markers were a well-defined DEJ and presence of mild/moderate but not severe epidermal dysplasia for AK, severe epidermal dysplasia and well-defined DEJ for SCCis, interrupted DEJ and/or dermal broad infiltrative strands for invasive SCC, dermal lobules connected and/or unconnected to the epidermis for BCC, as well as single atypical melanocytes and/or nest of atypical melanocytes in the epidermis or dermis for MM. This review compiles evidence on LC-OCT in dermato-oncology, providing a harmonized histopathology-integrated terminology and key image-markers for each lesion. Further evaluation is required to determine the clinical value of these findings.

KW - carcinoma, basal cell

KW - carcinoma, squamous cell

KW - keratosis, actinic

KW - melanoma

KW - microscopy, confocal

KW - optical coherence, tomography

KW - optical imaging

KW - review

KW - skin neoplasms

U2 - 10.1111/exd.15057

DO - 10.1111/exd.15057

M3 - Review

C2 - 38623958

AN - SCOPUS:85190414396

VL - 33

JO - Experimental Dermatology

JF - Experimental Dermatology

SN - 0906-6705

IS - 4

M1 - e15057

ER -

ID: 389458366