Early- and late-onset pelvic inflammatory disease among women with cervical Chlamydia trachomatis infection at the time of induced abortion--a follow-up study
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Standard
Early- and late-onset pelvic inflammatory disease among women with cervical Chlamydia trachomatis infection at the time of induced abortion--a follow-up study. / Sørensen, Jette Led; Thranov, I; Hoff, G; Dirach, J.
I: Infection: A Journal of Infectious Diseases, Bind 22, Nr. 4, 1994, s. 242-6.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Early- and late-onset pelvic inflammatory disease among women with cervical Chlamydia trachomatis infection at the time of induced abortion--a follow-up study
AU - Sørensen, Jette Led
AU - Thranov, I
AU - Hoff, G
AU - Dirach, J
PY - 1994
Y1 - 1994
N2 - After termination of a double-blind, randomized study on erythromycin in the prevention of post-abortion infection, 34 women (14 treated with erythromycin, 20 not treated with erythromycin) harbouring Chlamydia trachomatis were followed up within 6 weeks and again 2 to 24 months after the abortion in order to detect an early- and late-onset pelvic inflammatory disease (PID). For statistical analysis survival analysis by Kaplan-Meir estimates and Mantel-Cox test were carried out. Untreated women with C. trachomatis infection at the time of abortion had a cumulative risk of 72% of developing early and/or late PID, if observed for 24 months. This cumulative risk was significantly reduced to 8% if the C. trachomatis infection was treated at the time of the abortion. Screening for and treatment of C. trachomatis is warranted, especially in women <or = 25 years old, to avoid early and late-onset PID after induced first trimester abortion.
AB - After termination of a double-blind, randomized study on erythromycin in the prevention of post-abortion infection, 34 women (14 treated with erythromycin, 20 not treated with erythromycin) harbouring Chlamydia trachomatis were followed up within 6 weeks and again 2 to 24 months after the abortion in order to detect an early- and late-onset pelvic inflammatory disease (PID). For statistical analysis survival analysis by Kaplan-Meir estimates and Mantel-Cox test were carried out. Untreated women with C. trachomatis infection at the time of abortion had a cumulative risk of 72% of developing early and/or late PID, if observed for 24 months. This cumulative risk was significantly reduced to 8% if the C. trachomatis infection was treated at the time of the abortion. Screening for and treatment of C. trachomatis is warranted, especially in women <or = 25 years old, to avoid early and late-onset PID after induced first trimester abortion.
KW - Abortion, Induced
KW - Chlamydia Infections
KW - Chlamydia trachomatis
KW - Double-Blind Method
KW - Erythromycin
KW - Female
KW - Follow-Up Studies
KW - Humans
KW - Pelvic Inflammatory Disease
KW - Pregnancy
KW - Pregnancy Complications, Infectious
KW - Pregnancy Trimester, First
KW - Proportional Hazards Models
KW - Risk Factors
KW - Survival Analysis
KW - Time Factors
KW - Uterine Cervical Diseases
M3 - Journal article
C2 - 8002083
VL - 22
SP - 242
EP - 246
JO - Therapies
JF - Therapies
SN - 0300-8126
IS - 4
ER -
ID: 40461969