Abnormal echocardiography in patients with type 2 diabetes and relation to symptoms and clinical characteristics

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Abnormal echocardiography in patients with type 2 diabetes and relation to symptoms and clinical characteristics. / Jørgensen, Peter Godsk; Jensen, Magnus Thorsten; Mogelvang, Rasmus; von Scholten, Bernt Johan; Bech, Jan; Hansen, Thomas Fritz; Galatius, Søren; Biering-Sørensen, Tor; Andersen, Henrik Ullits; Lauritsen, Tina Vilsbøll; Rossing, Peter; Jensen, Jan Skov.

I: Diabetes and Vascular Disease Research, Bind 13, Nr. 5, 09.2016, s. 321-330.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Jørgensen, PG, Jensen, MT, Mogelvang, R, von Scholten, BJ, Bech, J, Hansen, TF, Galatius, S, Biering-Sørensen, T, Andersen, HU, Lauritsen, TV, Rossing, P & Jensen, JS 2016, 'Abnormal echocardiography in patients with type 2 diabetes and relation to symptoms and clinical characteristics', Diabetes and Vascular Disease Research, bind 13, nr. 5, s. 321-330. https://doi.org/10.1177/1479164116645583

APA

Jørgensen, P. G., Jensen, M. T., Mogelvang, R., von Scholten, B. J., Bech, J., Hansen, T. F., Galatius, S., Biering-Sørensen, T., Andersen, H. U., Lauritsen, T. V., Rossing, P., & Jensen, J. S. (2016). Abnormal echocardiography in patients with type 2 diabetes and relation to symptoms and clinical characteristics. Diabetes and Vascular Disease Research, 13(5), 321-330. https://doi.org/10.1177/1479164116645583

Vancouver

Jørgensen PG, Jensen MT, Mogelvang R, von Scholten BJ, Bech J, Hansen TF o.a. Abnormal echocardiography in patients with type 2 diabetes and relation to symptoms and clinical characteristics. Diabetes and Vascular Disease Research. 2016 sep.;13(5):321-330. https://doi.org/10.1177/1479164116645583

Author

Jørgensen, Peter Godsk ; Jensen, Magnus Thorsten ; Mogelvang, Rasmus ; von Scholten, Bernt Johan ; Bech, Jan ; Hansen, Thomas Fritz ; Galatius, Søren ; Biering-Sørensen, Tor ; Andersen, Henrik Ullits ; Lauritsen, Tina Vilsbøll ; Rossing, Peter ; Jensen, Jan Skov. / Abnormal echocardiography in patients with type 2 diabetes and relation to symptoms and clinical characteristics. I: Diabetes and Vascular Disease Research. 2016 ; Bind 13, Nr. 5. s. 321-330.

Bibtex

@article{48d944b935fd47598f29e9bcfa3f935b,
title = "Abnormal echocardiography in patients with type 2 diabetes and relation to symptoms and clinical characteristics",
abstract = "OBJECTIVES: We aimed to determine the prevalence of echocardiographic abnormalities and their relation to clinical characteristics and cardiac symptoms in a large, contemporary cohort of patients with type 2 diabetes.RESULTS: A total of 1030 patients with type 2 diabetes participated. Echocardiographic abnormalities were present in 513 (49.8%) patients, mainly driven by a high prevalence of diastolic dysfunction 178 (19.4%), left ventricular hypertrophy 213 (21.0%) and left atrial enlargement, 200 (19.6%). The prevalence increased markedly with age from 31.1% in the youngest group (<55 years) to 73.9% in the oldest group (>75 years) (p < 0.001) and was equally distributed among the sexes (p = 0.76). In univariate analyses, electrocardiographic abnormalities, age, body mass index, known coronary heart disease, hypertension, albuminuria, diabetes duration and creatinine were associated with abnormal echocardiography along with dyspnoea and characteristic chest pain (p < 0.05 for all). Neither of the cardiac symptoms nor clinical characteristics had sufficient sensitivity and specificity to accurately identify patients with abnormal echocardiography.CONCLUSION: Echocardiographic abnormalities are very common in outpatients with type 2 diabetes, but neither cardiac symptoms nor clinical characteristics are effective to identify patients with echocardiographic abnormalities.",
keywords = "Journal Article",
author = "J{\o}rgensen, {Peter Godsk} and Jensen, {Magnus Thorsten} and Rasmus Mogelvang and {von Scholten}, {Bernt Johan} and Jan Bech and Hansen, {Thomas Fritz} and S{\o}ren Galatius and Tor Biering-S{\o}rensen and Andersen, {Henrik Ullits} and Lauritsen, {Tina Vilsb{\o}ll} and Peter Rossing and Jensen, {Jan Skov}",
note = "{\textcopyright} The Author(s) 2016.",
year = "2016",
month = sep,
doi = "10.1177/1479164116645583",
language = "English",
volume = "13",
pages = "321--330",
journal = "Diabetes and Vascular Disease Research",
issn = "1479-1641",
publisher = "SAGE Publications",
number = "5",

}

RIS

TY - JOUR

T1 - Abnormal echocardiography in patients with type 2 diabetes and relation to symptoms and clinical characteristics

AU - Jørgensen, Peter Godsk

AU - Jensen, Magnus Thorsten

AU - Mogelvang, Rasmus

AU - von Scholten, Bernt Johan

AU - Bech, Jan

AU - Hansen, Thomas Fritz

AU - Galatius, Søren

AU - Biering-Sørensen, Tor

AU - Andersen, Henrik Ullits

AU - Lauritsen, Tina Vilsbøll

AU - Rossing, Peter

AU - Jensen, Jan Skov

N1 - © The Author(s) 2016.

PY - 2016/9

Y1 - 2016/9

N2 - OBJECTIVES: We aimed to determine the prevalence of echocardiographic abnormalities and their relation to clinical characteristics and cardiac symptoms in a large, contemporary cohort of patients with type 2 diabetes.RESULTS: A total of 1030 patients with type 2 diabetes participated. Echocardiographic abnormalities were present in 513 (49.8%) patients, mainly driven by a high prevalence of diastolic dysfunction 178 (19.4%), left ventricular hypertrophy 213 (21.0%) and left atrial enlargement, 200 (19.6%). The prevalence increased markedly with age from 31.1% in the youngest group (<55 years) to 73.9% in the oldest group (>75 years) (p < 0.001) and was equally distributed among the sexes (p = 0.76). In univariate analyses, electrocardiographic abnormalities, age, body mass index, known coronary heart disease, hypertension, albuminuria, diabetes duration and creatinine were associated with abnormal echocardiography along with dyspnoea and characteristic chest pain (p < 0.05 for all). Neither of the cardiac symptoms nor clinical characteristics had sufficient sensitivity and specificity to accurately identify patients with abnormal echocardiography.CONCLUSION: Echocardiographic abnormalities are very common in outpatients with type 2 diabetes, but neither cardiac symptoms nor clinical characteristics are effective to identify patients with echocardiographic abnormalities.

AB - OBJECTIVES: We aimed to determine the prevalence of echocardiographic abnormalities and their relation to clinical characteristics and cardiac symptoms in a large, contemporary cohort of patients with type 2 diabetes.RESULTS: A total of 1030 patients with type 2 diabetes participated. Echocardiographic abnormalities were present in 513 (49.8%) patients, mainly driven by a high prevalence of diastolic dysfunction 178 (19.4%), left ventricular hypertrophy 213 (21.0%) and left atrial enlargement, 200 (19.6%). The prevalence increased markedly with age from 31.1% in the youngest group (<55 years) to 73.9% in the oldest group (>75 years) (p < 0.001) and was equally distributed among the sexes (p = 0.76). In univariate analyses, electrocardiographic abnormalities, age, body mass index, known coronary heart disease, hypertension, albuminuria, diabetes duration and creatinine were associated with abnormal echocardiography along with dyspnoea and characteristic chest pain (p < 0.05 for all). Neither of the cardiac symptoms nor clinical characteristics had sufficient sensitivity and specificity to accurately identify patients with abnormal echocardiography.CONCLUSION: Echocardiographic abnormalities are very common in outpatients with type 2 diabetes, but neither cardiac symptoms nor clinical characteristics are effective to identify patients with echocardiographic abnormalities.

KW - Journal Article

U2 - 10.1177/1479164116645583

DO - 10.1177/1479164116645583

M3 - Journal article

C2 - 27208801

VL - 13

SP - 321

EP - 330

JO - Diabetes and Vascular Disease Research

JF - Diabetes and Vascular Disease Research

SN - 1479-1641

IS - 5

ER -

ID: 172821351