Acute changes in plasma glucose increases left ventricular systolic function in insulin-treated patients with type 2 diabetes and controls

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Standard

Acute changes in plasma glucose increases left ventricular systolic function in insulin-treated patients with type 2 diabetes and controls. / Andersen, Andreas; Jørgensen, Peter G.; Bagger, Jonatan; Baldassarre, Maria P. A.; Christensen, Mikkel B.; Pedersen-Bjergaard, Ulrik; Lindhardt, Tommi B.; Gislason, Gunnar; Knop, Filip K.; Vilsbøll, Tina.

I: Diabetes, Obesity and Metabolism, Bind 24, Nr. 6, 2022, s. 1123-1131.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Andersen, A, Jørgensen, PG, Bagger, J, Baldassarre, MPA, Christensen, MB, Pedersen-Bjergaard, U, Lindhardt, TB, Gislason, G, Knop, FK & Vilsbøll, T 2022, 'Acute changes in plasma glucose increases left ventricular systolic function in insulin-treated patients with type 2 diabetes and controls', Diabetes, Obesity and Metabolism, bind 24, nr. 6, s. 1123-1131. https://doi.org/10.1111/dom.14682

APA

Andersen, A., Jørgensen, P. G., Bagger, J., Baldassarre, M. P. A., Christensen, M. B., Pedersen-Bjergaard, U., Lindhardt, T. B., Gislason, G., Knop, F. K., & Vilsbøll, T. (2022). Acute changes in plasma glucose increases left ventricular systolic function in insulin-treated patients with type 2 diabetes and controls. Diabetes, Obesity and Metabolism, 24(6), 1123-1131. https://doi.org/10.1111/dom.14682

Vancouver

Andersen A, Jørgensen PG, Bagger J, Baldassarre MPA, Christensen MB, Pedersen-Bjergaard U o.a. Acute changes in plasma glucose increases left ventricular systolic function in insulin-treated patients with type 2 diabetes and controls. Diabetes, Obesity and Metabolism. 2022;24(6):1123-1131. https://doi.org/10.1111/dom.14682

Author

Andersen, Andreas ; Jørgensen, Peter G. ; Bagger, Jonatan ; Baldassarre, Maria P. A. ; Christensen, Mikkel B. ; Pedersen-Bjergaard, Ulrik ; Lindhardt, Tommi B. ; Gislason, Gunnar ; Knop, Filip K. ; Vilsbøll, Tina. / Acute changes in plasma glucose increases left ventricular systolic function in insulin-treated patients with type 2 diabetes and controls. I: Diabetes, Obesity and Metabolism. 2022 ; Bind 24, Nr. 6. s. 1123-1131.

Bibtex

@article{8adb8f2971274de0b06c9b39b1a0b041,
title = "Acute changes in plasma glucose increases left ventricular systolic function in insulin-treated patients with type 2 diabetes and controls",
abstract = "Aims We aimed to evaluate the effect of acute hyperglycaemia and hypoglycaemia on cardiac function in patients with type 2 diabetes (T2D) and a control group. Materials and methods In a nonrandomized interventional study, insulin-treated patients with T2D (N = 21, mean +/- SD age 62.8 +/- 6.5 years, body mass index [BMI] 29.0 +/- 4.2 kg/m(2), glycated haemoglobin [HbA1c] 51.0 +/- 5.4 mmol/mol [6.8 +/- 0.5%]) and matched controls (N = 21, mean +/- SD age 62.2 +/- 8.3 years, BMI 29.2 +/- 3.5 kg/m(2), HbA1c 34.3 +/- 3.3 mmol/L [5.3 +/- 0.3%]) underwent one experimental day with plasma glucose (PG) clamped at three different 30-minute steady-state levels: (1) fasting plasma glucose (FPG); (2) hyperglycaemia (FPG + 10 mmol/L); and (3) hyperinsulinaemic hypoglycaemia (PG",
keywords = "ACUTE HYPERGLYCEMIA, INDUCED HYPOGLYCEMIA, RESPONSES, RISK",
author = "Andreas Andersen and J{\o}rgensen, {Peter G.} and Jonatan Bagger and Baldassarre, {Maria P. A.} and Christensen, {Mikkel B.} and Ulrik Pedersen-Bjergaard and Lindhardt, {Tommi B.} and Gunnar Gislason and Knop, {Filip K.} and Tina Vilsb{\o}ll",
year = "2022",
doi = "10.1111/dom.14682",
language = "English",
volume = "24",
pages = "1123--1131",
journal = "Diabetes, Obesity and Metabolism",
issn = "1462-8902",
publisher = "Wiley-Blackwell",
number = "6",

}

RIS

TY - JOUR

T1 - Acute changes in plasma glucose increases left ventricular systolic function in insulin-treated patients with type 2 diabetes and controls

AU - Andersen, Andreas

AU - Jørgensen, Peter G.

AU - Bagger, Jonatan

AU - Baldassarre, Maria P. A.

AU - Christensen, Mikkel B.

AU - Pedersen-Bjergaard, Ulrik

AU - Lindhardt, Tommi B.

AU - Gislason, Gunnar

AU - Knop, Filip K.

AU - Vilsbøll, Tina

PY - 2022

Y1 - 2022

N2 - Aims We aimed to evaluate the effect of acute hyperglycaemia and hypoglycaemia on cardiac function in patients with type 2 diabetes (T2D) and a control group. Materials and methods In a nonrandomized interventional study, insulin-treated patients with T2D (N = 21, mean +/- SD age 62.8 +/- 6.5 years, body mass index [BMI] 29.0 +/- 4.2 kg/m(2), glycated haemoglobin [HbA1c] 51.0 +/- 5.4 mmol/mol [6.8 +/- 0.5%]) and matched controls (N = 21, mean +/- SD age 62.2 +/- 8.3 years, BMI 29.2 +/- 3.5 kg/m(2), HbA1c 34.3 +/- 3.3 mmol/L [5.3 +/- 0.3%]) underwent one experimental day with plasma glucose (PG) clamped at three different 30-minute steady-state levels: (1) fasting plasma glucose (FPG); (2) hyperglycaemia (FPG + 10 mmol/L); and (3) hyperinsulinaemic hypoglycaemia (PG

AB - Aims We aimed to evaluate the effect of acute hyperglycaemia and hypoglycaemia on cardiac function in patients with type 2 diabetes (T2D) and a control group. Materials and methods In a nonrandomized interventional study, insulin-treated patients with T2D (N = 21, mean +/- SD age 62.8 +/- 6.5 years, body mass index [BMI] 29.0 +/- 4.2 kg/m(2), glycated haemoglobin [HbA1c] 51.0 +/- 5.4 mmol/mol [6.8 +/- 0.5%]) and matched controls (N = 21, mean +/- SD age 62.2 +/- 8.3 years, BMI 29.2 +/- 3.5 kg/m(2), HbA1c 34.3 +/- 3.3 mmol/L [5.3 +/- 0.3%]) underwent one experimental day with plasma glucose (PG) clamped at three different 30-minute steady-state levels: (1) fasting plasma glucose (FPG); (2) hyperglycaemia (FPG + 10 mmol/L); and (3) hyperinsulinaemic hypoglycaemia (PG

KW - ACUTE HYPERGLYCEMIA

KW - INDUCED HYPOGLYCEMIA

KW - RESPONSES

KW - RISK

U2 - 10.1111/dom.14682

DO - 10.1111/dom.14682

M3 - Journal article

C2 - 35238140

VL - 24

SP - 1123

EP - 1131

JO - Diabetes, Obesity and Metabolism

JF - Diabetes, Obesity and Metabolism

SN - 1462-8902

IS - 6

ER -

ID: 301705037