Defective amplification of the late phase insulin response to glucose by GIP in obese Type II diabetic patients
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Defective amplification of the late phase insulin response to glucose by GIP in obese Type II diabetic patients. / Vilsbøll, Tina; Krarup, T; Madsbad, S; Holst, Jens Møller.
I: Diabetologia, Bind 45, Nr. 8, 01.08.2002, s. 1111-9.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Defective amplification of the late phase insulin response to glucose by GIP in obese Type II diabetic patients
AU - Vilsbøll, Tina
AU - Krarup, T
AU - Madsbad, S
AU - Holst, Jens Møller
PY - 2002/8/1
Y1 - 2002/8/1
N2 - Glucagon-like-peptide-1 (GLP-1) is strongly insulinotropic in patients with Type II (non-insulin-dependent) diabetes mellitus, whereas glucose-dependent insulinotropic polypeptide (GIP) is less effective. Our investigation evaluated "early" (protocol 1) - and "late phase" (protocol 2) insulin and C-peptide responses to GLP-1 and GIP stimulation in patients with Type II diabetes.
AB - Glucagon-like-peptide-1 (GLP-1) is strongly insulinotropic in patients with Type II (non-insulin-dependent) diabetes mellitus, whereas glucose-dependent insulinotropic polypeptide (GIP) is less effective. Our investigation evaluated "early" (protocol 1) - and "late phase" (protocol 2) insulin and C-peptide responses to GLP-1 and GIP stimulation in patients with Type II diabetes.
U2 - http://dx.doi.org/10.1007/s00125-002-0878-6
DO - http://dx.doi.org/10.1007/s00125-002-0878-6
M3 - Journal article
VL - 45
SP - 1111
EP - 1119
JO - Diabetologia
JF - Diabetologia
SN - 0012-186X
IS - 8
ER -
ID: 34069971