Semaglutide for the treatment of antipsychotic-associated weight gain in patients not responding to metformin - a case series

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Standard

Semaglutide for the treatment of antipsychotic-associated weight gain in patients not responding to metformin - a case series. / Prasad, Femin; De, Riddhita; Korann, Vittal; Chintoh, Araba F.; Remington, Gary; Ebdrup, Bjørn H.; Siskind, Dan; Knop, Filip Krag; Vilsbøll, Tina; Fink-Jensen, Anders; Hahn, Margaret K.; Agarwal, Sri Mahavir.

I: Therapeutic Advances in Psychopharmacology, Bind 13, 20451253231165169, 2023.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Prasad, F, De, R, Korann, V, Chintoh, AF, Remington, G, Ebdrup, BH, Siskind, D, Knop, FK, Vilsbøll, T, Fink-Jensen, A, Hahn, MK & Agarwal, SM 2023, 'Semaglutide for the treatment of antipsychotic-associated weight gain in patients not responding to metformin - a case series', Therapeutic Advances in Psychopharmacology, bind 13, 20451253231165169. https://doi.org/10.1177/20451253231165169

APA

Prasad, F., De, R., Korann, V., Chintoh, A. F., Remington, G., Ebdrup, B. H., Siskind, D., Knop, F. K., Vilsbøll, T., Fink-Jensen, A., Hahn, M. K., & Agarwal, S. M. (2023). Semaglutide for the treatment of antipsychotic-associated weight gain in patients not responding to metformin - a case series. Therapeutic Advances in Psychopharmacology, 13, [20451253231165169]. https://doi.org/10.1177/20451253231165169

Vancouver

Prasad F, De R, Korann V, Chintoh AF, Remington G, Ebdrup BH o.a. Semaglutide for the treatment of antipsychotic-associated weight gain in patients not responding to metformin - a case series. Therapeutic Advances in Psychopharmacology. 2023;13. 20451253231165169. https://doi.org/10.1177/20451253231165169

Author

Prasad, Femin ; De, Riddhita ; Korann, Vittal ; Chintoh, Araba F. ; Remington, Gary ; Ebdrup, Bjørn H. ; Siskind, Dan ; Knop, Filip Krag ; Vilsbøll, Tina ; Fink-Jensen, Anders ; Hahn, Margaret K. ; Agarwal, Sri Mahavir. / Semaglutide for the treatment of antipsychotic-associated weight gain in patients not responding to metformin - a case series. I: Therapeutic Advances in Psychopharmacology. 2023 ; Bind 13.

Bibtex

@article{9e81be9347e340be802edd308a69a9dc,
title = "Semaglutide for the treatment of antipsychotic-associated weight gain in patients not responding to metformin - a case series",
abstract = "Metformin is the currently accepted first-line treatment for antipsychotic-associated weight gain (AAWG). However, not all patients benefit from metformin. Glucagon-like peptide-1 receptor agonists (GLP1-RA) have shown promise in the management of obesity in the general population, with preliminary evidence supporting efficacy in AAWG. Semaglutide is a weekly injectable GLP-1RA which received recent approval for obesity management and noted superiority over other GLP-1RAs. This study explored the efficacy and tolerability of semaglutide in AAWG among individuals with severe mental illness. A retrospective chart review of patients treated with semaglutide in the Metabolic Clinic at the Center for Addiction and Mental Health (CAMH) between 2019 and 2021 was conducted. Patients failing a trial of metformin (",
keywords = "antipsychotics, metformin, obesity, semaglutide, severe mental illness, ONCE-WEEKLY SEMAGLUTIDE, PHASE 3A, OPEN-LABEL, DOUBLE-BLIND, ADD-ON, JAPANESE PATIENTS, DAILY SITAGLIPTIN, ORAL SEMAGLUTIDE, DIABETES CARE, DOUBLE-DUMMY",
author = "Femin Prasad and Riddhita De and Vittal Korann and Chintoh, {Araba F.} and Gary Remington and Ebdrup, {Bj{\o}rn H.} and Dan Siskind and Knop, {Filip Krag} and Tina Vilsb{\o}ll and Anders Fink-Jensen and Hahn, {Margaret K.} and Agarwal, {Sri Mahavir}",
year = "2023",
doi = "10.1177/20451253231165169",
language = "English",
volume = "13",
journal = "Therapeutic Advances in Psychopharmacology",
issn = "2045-1253",
publisher = "SAGE Publications",

}

RIS

TY - JOUR

T1 - Semaglutide for the treatment of antipsychotic-associated weight gain in patients not responding to metformin - a case series

AU - Prasad, Femin

AU - De, Riddhita

AU - Korann, Vittal

AU - Chintoh, Araba F.

AU - Remington, Gary

AU - Ebdrup, Bjørn H.

AU - Siskind, Dan

AU - Knop, Filip Krag

AU - Vilsbøll, Tina

AU - Fink-Jensen, Anders

AU - Hahn, Margaret K.

AU - Agarwal, Sri Mahavir

PY - 2023

Y1 - 2023

N2 - Metformin is the currently accepted first-line treatment for antipsychotic-associated weight gain (AAWG). However, not all patients benefit from metformin. Glucagon-like peptide-1 receptor agonists (GLP1-RA) have shown promise in the management of obesity in the general population, with preliminary evidence supporting efficacy in AAWG. Semaglutide is a weekly injectable GLP-1RA which received recent approval for obesity management and noted superiority over other GLP-1RAs. This study explored the efficacy and tolerability of semaglutide in AAWG among individuals with severe mental illness. A retrospective chart review of patients treated with semaglutide in the Metabolic Clinic at the Center for Addiction and Mental Health (CAMH) between 2019 and 2021 was conducted. Patients failing a trial of metformin (

AB - Metformin is the currently accepted first-line treatment for antipsychotic-associated weight gain (AAWG). However, not all patients benefit from metformin. Glucagon-like peptide-1 receptor agonists (GLP1-RA) have shown promise in the management of obesity in the general population, with preliminary evidence supporting efficacy in AAWG. Semaglutide is a weekly injectable GLP-1RA which received recent approval for obesity management and noted superiority over other GLP-1RAs. This study explored the efficacy and tolerability of semaglutide in AAWG among individuals with severe mental illness. A retrospective chart review of patients treated with semaglutide in the Metabolic Clinic at the Center for Addiction and Mental Health (CAMH) between 2019 and 2021 was conducted. Patients failing a trial of metformin (

KW - antipsychotics

KW - metformin

KW - obesity

KW - semaglutide

KW - severe mental illness

KW - ONCE-WEEKLY SEMAGLUTIDE

KW - PHASE 3A

KW - OPEN-LABEL

KW - DOUBLE-BLIND

KW - ADD-ON

KW - JAPANESE PATIENTS

KW - DAILY SITAGLIPTIN

KW - ORAL SEMAGLUTIDE

KW - DIABETES CARE

KW - DOUBLE-DUMMY

U2 - 10.1177/20451253231165169

DO - 10.1177/20451253231165169

M3 - Journal article

C2 - 37113745

VL - 13

JO - Therapeutic Advances in Psychopharmacology

JF - Therapeutic Advances in Psychopharmacology

SN - 2045-1253

M1 - 20451253231165169

ER -

ID: 347979678