Regulering af cytokindannelse ved inflammatoriske tarmsygdomme
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Regulering af cytokindannelse ved inflammatoriske tarmsygdomme. / Ferrero-Miliani, Laura; Seidelin, Jakob Benecidt; Nielsen, Ole Haagen.
I: Ugeskrift for Laeger, Bind 168, Nr. 19, 08.05.2006, s. 1847-50.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Regulering af cytokindannelse ved inflammatoriske tarmsygdomme
AU - Ferrero-Miliani, Laura
AU - Seidelin, Jakob Benecidt
AU - Nielsen, Ole Haagen
PY - 2006/5/8
Y1 - 2006/5/8
N2 - Interleukin-1beta (IL-1beta) is a pivotal mediator in the inflammatory immune response that is characteristic of a number of chronic disorders. The etiology and pathophysiology of inflammatory bowel disease (IBD) have for many years been an enigma. The recent identification of the inflammasome, a multiprotein complex responsible for interleukin-1beta converting enzyme (ICE, caspase-1) activation, has generated new possibilities for the elucidation of the etiology and pathophysiology of IBD and as a consequence also for the identification of new treatment targets.
AB - Interleukin-1beta (IL-1beta) is a pivotal mediator in the inflammatory immune response that is characteristic of a number of chronic disorders. The etiology and pathophysiology of inflammatory bowel disease (IBD) have for many years been an enigma. The recent identification of the inflammasome, a multiprotein complex responsible for interleukin-1beta converting enzyme (ICE, caspase-1) activation, has generated new possibilities for the elucidation of the etiology and pathophysiology of IBD and as a consequence also for the identification of new treatment targets.
KW - Caspase 1
KW - Colitis, Ulcerative
KW - Cytokines
KW - Enzyme Activation
KW - Humans
KW - Multiprotein Complexes
KW - English Abstract
KW - Journal Article
KW - Review
M3 - Tidsskriftartikel
C2 - 16756799
VL - 168
SP - 1847
EP - 1850
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 19
ER -
ID: 173051383