A Test in Context - Klinisk biokemi

Institut for Klinisk Medicin

A Test in Context: Lipid Profile, Fasting Versus Nonfasting

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Standard

A Test in Context : Lipid Profile, Fasting Versus Nonfasting. / Nordestgaard, Børge G.

I: Journal of the American College of Cardiology, Bind 70, Nr. 13, 09.2017, s. 1637-1646.

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Harvard

Nordestgaard, BG 2017, 'A Test in Context: Lipid Profile, Fasting Versus Nonfasting', Journal of the American College of Cardiology, bind 70, nr. 13, s. 1637-1646. https://doi.org/10.1016/j.jacc.2017.08.006

APA

Nordestgaard, B. G. (2017). A Test in Context: Lipid Profile, Fasting Versus Nonfasting. Journal of the American College of Cardiology, 70(13), 1637-1646. https://doi.org/10.1016/j.jacc.2017.08.006

Vancouver

Nordestgaard BG. A Test in Context: Lipid Profile, Fasting Versus Nonfasting. Journal of the American College of Cardiology. 2017 sep.;70(13):1637-1646. https://doi.org/10.1016/j.jacc.2017.08.006

Author

Nordestgaard, Børge G. / A Test in Context : Lipid Profile, Fasting Versus Nonfasting. I: Journal of the American College of Cardiology. 2017 ; Bind 70, Nr. 13. s. 1637-1646.

Bibtex

@article{5f274ad7dde04a5ab3c417f272a98cbc,

title = "A Test in Context: Lipid Profile, Fasting Versus Nonfasting",

abstract = "Fasting for >8 h, as previously required for lipid profiles, normally only occurs a few hours before breakfast. By contrast, the nonfasting state predominates most of a 24-h cycle and better captures atherogenic lipoprotein levels. Plasma contains atherogenic lipoproteins of hepatic origin in the fasting state and additionally those of intestinal origin in the nonfasting state. Maximal mean changes for random, nonfasting versus fasting levels are +26 mg/dl for triglycerides, -8 mg/dl for total cholesterol, -8 mg/dl for low-density lipoprotein cholesterol, +8 mg/dl for remnant cholesterol, and -8 mg/dl for non-high-density lipoprotein cholesterol; lipoprotein(a), apolipoprotein B, and high-density lipoprotein cholesterol are largely unaffected. For patients, laboratories, and clinicians alike, nonfasting lipid profiles represent a simplification without negative implications for prognostic, diagnostic, and therapeutic options for cardiovascular disease prevention. Several societies' guidelines and statements in Denmark, the United Kingdom, Europe, Canada, Brazil, and the United States endorse nonfasting lipid profiles.",

keywords = "Cardiovascular Diseases, Dyslipidemias, Fasting, Humans, Lipids, Reproducibility of Results, Journal Article, Review",

author = "Nordestgaard, {B{\o}rge G}",

year = "2017",

month = sep,

doi = "10.1016/j.jacc.2017.08.006",

language = "English",

volume = "70",

pages = "1637--1646",

journal = "Journal of the American College of Cardiology",

issn = "0735-1097",

publisher = "Elsevier",

number = "13",

}

RIS

TY - JOUR

T1 - A Test in Context

T2 - Lipid Profile, Fasting Versus Nonfasting

AU - Nordestgaard, Børge G

PY - 2017/9

Y1 - 2017/9

N2 - Fasting for >8 h, as previously required for lipid profiles, normally only occurs a few hours before breakfast. By contrast, the nonfasting state predominates most of a 24-h cycle and better captures atherogenic lipoprotein levels. Plasma contains atherogenic lipoproteins of hepatic origin in the fasting state and additionally those of intestinal origin in the nonfasting state. Maximal mean changes for random, nonfasting versus fasting levels are +26 mg/dl for triglycerides, -8 mg/dl for total cholesterol, -8 mg/dl for low-density lipoprotein cholesterol, +8 mg/dl for remnant cholesterol, and -8 mg/dl for non-high-density lipoprotein cholesterol; lipoprotein(a), apolipoprotein B, and high-density lipoprotein cholesterol are largely unaffected. For patients, laboratories, and clinicians alike, nonfasting lipid profiles represent a simplification without negative implications for prognostic, diagnostic, and therapeutic options for cardiovascular disease prevention. Several societies' guidelines and statements in Denmark, the United Kingdom, Europe, Canada, Brazil, and the United States endorse nonfasting lipid profiles.

AB - Fasting for >8 h, as previously required for lipid profiles, normally only occurs a few hours before breakfast. By contrast, the nonfasting state predominates most of a 24-h cycle and better captures atherogenic lipoprotein levels. Plasma contains atherogenic lipoproteins of hepatic origin in the fasting state and additionally those of intestinal origin in the nonfasting state. Maximal mean changes for random, nonfasting versus fasting levels are +26 mg/dl for triglycerides, -8 mg/dl for total cholesterol, -8 mg/dl for low-density lipoprotein cholesterol, +8 mg/dl for remnant cholesterol, and -8 mg/dl for non-high-density lipoprotein cholesterol; lipoprotein(a), apolipoprotein B, and high-density lipoprotein cholesterol are largely unaffected. For patients, laboratories, and clinicians alike, nonfasting lipid profiles represent a simplification without negative implications for prognostic, diagnostic, and therapeutic options for cardiovascular disease prevention. Several societies' guidelines and statements in Denmark, the United Kingdom, Europe, Canada, Brazil, and the United States endorse nonfasting lipid profiles.

KW - Cardiovascular Diseases

KW - Dyslipidemias

KW - Fasting

KW - Humans

KW - Lipids

KW - Reproducibility of Results

KW - Journal Article

KW - Review

U2 - 10.1016/j.jacc.2017.08.006

DO - 10.1016/j.jacc.2017.08.006

M3 - Review

C2 - 28935041

VL - 70

SP - 1637

EP - 1646

JO - Journal of the American College of Cardiology

JF - Journal of the American College of Cardiology

SN - 0735-1097

IS - 13

ER -

ID: 185870853