Use of Lipoprotein(a) in clinical practice: A biomarker whose time has come. A scientific statement from the National Lipid Association: Corrigendum/New version to Journal of Clinical Lipidology (2019) 13(3) (374–392), (S1933287419300868), (10.1016/j.jacl.2019.04.010))
Publikation: Bidrag til tidsskrift › Kommentar/debat › Forskning › fagfællebedømt
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Use of Lipoprotein(a) in clinical practice: A biomarker whose time has come. A scientific statement from the National Lipid Association : Corrigendum/New version to Journal of Clinical Lipidology (2019) 13(3) (374–392), (S1933287419300868), (10.1016/j.jacl.2019.04.010)). / Wilson, Don P.; Jacobson, Terry A.; Jones, Peter H.; Koschinsky, Marlys L.; McNeal, Catherine J.; Nordestgaard, Børge G.; Orringer, Carl E.
I: Journal of Clinical Lipidology, Bind 16, Nr. 5, 01.09.2022, s. e77-e95.Publikation: Bidrag til tidsskrift › Kommentar/debat › Forskning › fagfællebedømt
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TY - JOUR
T1 - Use of Lipoprotein(a) in clinical practice: A biomarker whose time has come. A scientific statement from the National Lipid Association
T2 - Corrigendum/New version to Journal of Clinical Lipidology (2019) 13(3) (374–392), (S1933287419300868), (10.1016/j.jacl.2019.04.010))
AU - Wilson, Don P.
AU - Jacobson, Terry A.
AU - Jones, Peter H.
AU - Koschinsky, Marlys L.
AU - McNeal, Catherine J.
AU - Nordestgaard, Børge G.
AU - Orringer, Carl E.
N1 - Publisher Copyright: © 2022 National Lipid Association
PY - 2022/9/1
Y1 - 2022/9/1
N2 - Lipoprotein(a) [Lp(a)] is a well-recognized, independent risk factor for atherosclerotic cardiovascular disease, with elevated levels estimated to be prevalent in 20% of the population. Observational and genetic evidence strongly support a causal relationship between high plasma concentrations of Lp(a) and increased risk of atherosclerotic cardiovascular disease–related events, such as myocardial infarction and stroke, and valvular aortic stenosis. In this scientific statement, we review an array of evidence-based considerations for testing of Lp(a) in clinical practice and the utilization of Lp(a) levels to inform treatment strategies in primary and secondary prevention.
AB - Lipoprotein(a) [Lp(a)] is a well-recognized, independent risk factor for atherosclerotic cardiovascular disease, with elevated levels estimated to be prevalent in 20% of the population. Observational and genetic evidence strongly support a causal relationship between high plasma concentrations of Lp(a) and increased risk of atherosclerotic cardiovascular disease–related events, such as myocardial infarction and stroke, and valvular aortic stenosis. In this scientific statement, we review an array of evidence-based considerations for testing of Lp(a) in clinical practice and the utilization of Lp(a) levels to inform treatment strategies in primary and secondary prevention.
KW - Atherosclerotic cardiovascular disease
KW - Biomarker
KW - Calcific valvular aortic disease
KW - Cardiovascular risk
KW - Coronary heart disease
KW - Cut points
KW - Lifestyle
KW - Lipoprotein(a)
KW - Lp(a)
KW - Myocardial infarction
KW - Primary prevention
KW - Scientific statement
KW - Secondary prevention
KW - Stroke
KW - Treatment
UR - http://www.scopus.com/inward/record.url?scp=85138571012&partnerID=8YFLogxK
U2 - 10.1016/j.jacl.2022.08.007
DO - 10.1016/j.jacl.2022.08.007
M3 - Comment/debate
C2 - 36068139
AN - SCOPUS:85138571012
VL - 16
SP - e77-e95
JO - Journal of Clinical Lipidology
JF - Journal of Clinical Lipidology
SN - 1933-2874
IS - 5
ER -
ID: 346781700