Intravenøs eller oral N-acetylcysteinbehandling til paracetamolforgiftede patienter. Er det tid til at revurdere behandlingsinstruksen?

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Standard

Intravenøs eller oral N-acetylcysteinbehandling til paracetamolforgiftede patienter. Er det tid til at revurdere behandlingsinstruksen? / Rolff, Hans Christian; Christensen, Hanne Rolighed; Dalhoff, Kim.

I: Ugeskrift for Laeger, Bind 172, Nr. 13, 2010, s. 1020-4.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Rolff, HC, Christensen, HR & Dalhoff, K 2010, 'Intravenøs eller oral N-acetylcysteinbehandling til paracetamolforgiftede patienter. Er det tid til at revurdere behandlingsinstruksen?', Ugeskrift for Laeger, bind 172, nr. 13, s. 1020-4.

APA

Rolff, H. C., Christensen, H. R., & Dalhoff, K. (2010). Intravenøs eller oral N-acetylcysteinbehandling til paracetamolforgiftede patienter. Er det tid til at revurdere behandlingsinstruksen? Ugeskrift for Laeger, 172(13), 1020-4.

Vancouver

Rolff HC, Christensen HR, Dalhoff K. Intravenøs eller oral N-acetylcysteinbehandling til paracetamolforgiftede patienter. Er det tid til at revurdere behandlingsinstruksen? Ugeskrift for Laeger. 2010;172(13):1020-4.

Author

Rolff, Hans Christian ; Christensen, Hanne Rolighed ; Dalhoff, Kim. / Intravenøs eller oral N-acetylcysteinbehandling til paracetamolforgiftede patienter. Er det tid til at revurdere behandlingsinstruksen?. I: Ugeskrift for Laeger. 2010 ; Bind 172, Nr. 13. s. 1020-4.

Bibtex

@article{630cf8546e3647f787dcdf6962ba8321,
title = "Intraven{\o}s eller oral N-acetylcysteinbehandling til paracetamolforgiftede patienter. Er det tid til at revurdere behandlingsinstruksen?",
abstract = "Danish paracetamol (PCM) poisoned patients are treated with N-acetylcysteine (NAC) intravenously for 36 hours. This probably leads to overtreatment. Today, patients with poor prognoses can be identified and, in addition, NAC may have serious side effects. We reviewed the literature (route of administration, duration and timing of treatment) and found that intravenous NAC often leads to side effects (some serious), primarily when serum paracetamol is low. These patients are often only mildly poisoned and they may therefore benefit from a shorter, orally administered regimen (equally efficient and with fewer side effects than intravenously administered NAC).",
author = "Rolff, {Hans Christian} and Christensen, {Hanne Rolighed} and Kim Dalhoff",
year = "2010",
language = "Dansk",
volume = "172",
pages = "1020--4",
journal = "Ugeskrift for Laeger",
issn = "0041-5782",
publisher = "Almindelige Danske Laegeforening",
number = "13",

}

RIS

TY - JOUR

T1 - Intravenøs eller oral N-acetylcysteinbehandling til paracetamolforgiftede patienter. Er det tid til at revurdere behandlingsinstruksen?

AU - Rolff, Hans Christian

AU - Christensen, Hanne Rolighed

AU - Dalhoff, Kim

PY - 2010

Y1 - 2010

N2 - Danish paracetamol (PCM) poisoned patients are treated with N-acetylcysteine (NAC) intravenously for 36 hours. This probably leads to overtreatment. Today, patients with poor prognoses can be identified and, in addition, NAC may have serious side effects. We reviewed the literature (route of administration, duration and timing of treatment) and found that intravenous NAC often leads to side effects (some serious), primarily when serum paracetamol is low. These patients are often only mildly poisoned and they may therefore benefit from a shorter, orally administered regimen (equally efficient and with fewer side effects than intravenously administered NAC).

AB - Danish paracetamol (PCM) poisoned patients are treated with N-acetylcysteine (NAC) intravenously for 36 hours. This probably leads to overtreatment. Today, patients with poor prognoses can be identified and, in addition, NAC may have serious side effects. We reviewed the literature (route of administration, duration and timing of treatment) and found that intravenous NAC often leads to side effects (some serious), primarily when serum paracetamol is low. These patients are often only mildly poisoned and they may therefore benefit from a shorter, orally administered regimen (equally efficient and with fewer side effects than intravenously administered NAC).

M3 - Tidsskriftartikel

VL - 172

SP - 1020

EP - 1024

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

SN - 0041-5782

IS - 13

ER -

ID: 40147610