Causes of Death in People with Dementia from 2002 to 2015: A Nationwide Study
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Causes of Death in People with Dementia from 2002 to 2015 : A Nationwide Study. / Taudorf, Lærke; Nørgaard, Ane; Islamoska, Sabrina; Laursen, Thomas Munk; Waldemar, Gunhild.
I: Journal of Alzheimer's Disease, Bind 82, Nr. 4, 2021, s. 1609-1618.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Causes of Death in People with Dementia from 2002 to 2015
T2 - A Nationwide Study
AU - Taudorf, Lærke
AU - Nørgaard, Ane
AU - Islamoska, Sabrina
AU - Laursen, Thomas Munk
AU - Waldemar, Gunhild
PY - 2021
Y1 - 2021
N2 - BACKGROUND: Dementia is associated with increased mortality. However, it is not clear whether causes of death in people with dementia have changed over time.OBJECTIVE: To investigate if causes of death changed over time in people with dementia compared to the general elderly population.METHODS: We included longitudinal data from nationwide registries on all Danish residents aged≥65 years to 110 years who died between 2002 to 2015. We assessed the annual frequency of dementia-related deaths (defined as a dementia diagnosis registered as a cause of death) and of underlying causes of death in people registered with dementia compared to the general elderly population.RESULTS: From 2002 to 2015, 621,826 people died, of whom 103,785 were diagnosed with dementia. During this period, the percentage of dementia-related deaths increased from 10.1% to 15.2% in women, and from 6.3% to 9.5% in men in the general elderly population. From 2002 to 2015, dementia became the leading, registered underlying cause of death in people diagnosed with dementia. Simultaneously, a marked decline in cardiovascular and cerebrovascular deaths was observed in people with and without dementia.CONCLUSION: This is the first study to investigate if the causes of death change over time in people diagnosed with dementia compared with the general elderly population. The increase in the registration of dementia as an underlying cause of death could reflect increasing awareness that dementia is fatal.
AB - BACKGROUND: Dementia is associated with increased mortality. However, it is not clear whether causes of death in people with dementia have changed over time.OBJECTIVE: To investigate if causes of death changed over time in people with dementia compared to the general elderly population.METHODS: We included longitudinal data from nationwide registries on all Danish residents aged≥65 years to 110 years who died between 2002 to 2015. We assessed the annual frequency of dementia-related deaths (defined as a dementia diagnosis registered as a cause of death) and of underlying causes of death in people registered with dementia compared to the general elderly population.RESULTS: From 2002 to 2015, 621,826 people died, of whom 103,785 were diagnosed with dementia. During this period, the percentage of dementia-related deaths increased from 10.1% to 15.2% in women, and from 6.3% to 9.5% in men in the general elderly population. From 2002 to 2015, dementia became the leading, registered underlying cause of death in people diagnosed with dementia. Simultaneously, a marked decline in cardiovascular and cerebrovascular deaths was observed in people with and without dementia.CONCLUSION: This is the first study to investigate if the causes of death change over time in people diagnosed with dementia compared with the general elderly population. The increase in the registration of dementia as an underlying cause of death could reflect increasing awareness that dementia is fatal.
U2 - 10.3233/JAD-201400
DO - 10.3233/JAD-201400
M3 - Journal article
C2 - 34180412
VL - 82
SP - 1609
EP - 1618
JO - Journal of Alzheimer's Disease
JF - Journal of Alzheimer's Disease
SN - 1387-2877
IS - 4
ER -
ID: 278280753