Fibrinogen: A potential biomarker for predicting disease severity in multiple sclerosis.

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Standard

Fibrinogen : A potential biomarker for predicting disease severity in multiple sclerosis. / Ahmad, Usman; Frederiksen, Jette Lautrup.

I: Multiple Sclerosis and Related Disorders, Bind 46, 102509, 2020.

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Harvard

Ahmad, U & Frederiksen, JL 2020, 'Fibrinogen: A potential biomarker for predicting disease severity in multiple sclerosis.', Multiple Sclerosis and Related Disorders, bind 46, 102509. https://doi.org/10.1016/j.msard.2020.102509

APA

Ahmad, U., & Frederiksen, J. L. (2020). Fibrinogen: A potential biomarker for predicting disease severity in multiple sclerosis. Multiple Sclerosis and Related Disorders, 46, [102509]. https://doi.org/10.1016/j.msard.2020.102509

Vancouver

Ahmad U, Frederiksen JL. Fibrinogen: A potential biomarker for predicting disease severity in multiple sclerosis. Multiple Sclerosis and Related Disorders. 2020;46. 102509. https://doi.org/10.1016/j.msard.2020.102509

Author

Ahmad, Usman ; Frederiksen, Jette Lautrup. / Fibrinogen : A potential biomarker for predicting disease severity in multiple sclerosis. I: Multiple Sclerosis and Related Disorders. 2020 ; Bind 46.

Bibtex

@article{2a7696701bd64e9a914dfce2c6e04440,
title = "Fibrinogen: A potential biomarker for predicting disease severity in multiple sclerosis.",
abstract = "Background: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system. The exact pathogenesis behind the development of MS is unknown. This study aims to elucidate the role of fibrinogen in MS pathology and discuss candidacy as a biomarker for disease management. Method: The method applied is a systematic literature review on the bio-medical database PubMed. Results: This study found that even though the role of fibrinogen in disease development has been studied considerably, clinical application as a viable biomarker has not yet been achieved conclusively in human studies. Conclusion: Recent evidence points toward fibrinogen and its degradation products playing a possible role in the disease pathogenesis Further research is needed to convincingly evaluate fibrinogen as a practical biomarker for diagnostic use or for assessing disease severity.",
keywords = "Blood, Cerebrospinal fluid, Diagnosis, Fibrin, Fibrinogen, Immunology, Multiple sclerosis, Prognostic use, Therapeutic use",
author = "Usman Ahmad and Frederiksen, {Jette Lautrup}",
year = "2020",
doi = "10.1016/j.msard.2020.102509",
language = "English",
volume = "46",
journal = "Multiple Sclerosis and Related Disorders",
issn = "2211-0348",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Fibrinogen

T2 - A potential biomarker for predicting disease severity in multiple sclerosis.

AU - Ahmad, Usman

AU - Frederiksen, Jette Lautrup

PY - 2020

Y1 - 2020

N2 - Background: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system. The exact pathogenesis behind the development of MS is unknown. This study aims to elucidate the role of fibrinogen in MS pathology and discuss candidacy as a biomarker for disease management. Method: The method applied is a systematic literature review on the bio-medical database PubMed. Results: This study found that even though the role of fibrinogen in disease development has been studied considerably, clinical application as a viable biomarker has not yet been achieved conclusively in human studies. Conclusion: Recent evidence points toward fibrinogen and its degradation products playing a possible role in the disease pathogenesis Further research is needed to convincingly evaluate fibrinogen as a practical biomarker for diagnostic use or for assessing disease severity.

AB - Background: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system. The exact pathogenesis behind the development of MS is unknown. This study aims to elucidate the role of fibrinogen in MS pathology and discuss candidacy as a biomarker for disease management. Method: The method applied is a systematic literature review on the bio-medical database PubMed. Results: This study found that even though the role of fibrinogen in disease development has been studied considerably, clinical application as a viable biomarker has not yet been achieved conclusively in human studies. Conclusion: Recent evidence points toward fibrinogen and its degradation products playing a possible role in the disease pathogenesis Further research is needed to convincingly evaluate fibrinogen as a practical biomarker for diagnostic use or for assessing disease severity.

KW - Blood

KW - Cerebrospinal fluid

KW - Diagnosis

KW - Fibrin

KW - Fibrinogen

KW - Immunology

KW - Multiple sclerosis

KW - Prognostic use

KW - Therapeutic use

U2 - 10.1016/j.msard.2020.102509

DO - 10.1016/j.msard.2020.102509

M3 - Review

C2 - 32977072

AN - SCOPUS:85091210925

VL - 46

JO - Multiple Sclerosis and Related Disorders

JF - Multiple Sclerosis and Related Disorders

SN - 2211-0348

M1 - 102509

ER -

ID: 260691964