Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a L150P mutation in PSEN-1

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Standard

Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a L150P mutation in PSEN-1. / Tubsuwan, Alisa; Pires, Carlota; Rasmussen, Mikkel A.; Schmid, Benjamin; Nielsen, Jørgen Erik; Hjermind, Lena Elisabeth; Hall, Vanessa Jane; Nielsen, Troels Tolstrup; Waldemar, Gunhild; Hyttel, Poul; Clausen, Christian; Kitiyanant, Narisorn; Freude, Kristine; Holst, Bjørn.

I: Stem Cell Research, Bind 16, Nr. 1, 01.2016, s. 110-112.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Tubsuwan, A, Pires, C, Rasmussen, MA, Schmid, B, Nielsen, JE, Hjermind, LE, Hall, VJ, Nielsen, TT, Waldemar, G, Hyttel, P, Clausen, C, Kitiyanant, N, Freude, K & Holst, B 2016, 'Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a L150P mutation in PSEN-1', Stem Cell Research, bind 16, nr. 1, s. 110-112. https://doi.org/10.1016/j.scr.2015.12.015

APA

Tubsuwan, A., Pires, C., Rasmussen, M. A., Schmid, B., Nielsen, J. E., Hjermind, L. E., Hall, V. J., Nielsen, T. T., Waldemar, G., Hyttel, P., Clausen, C., Kitiyanant, N., Freude, K., & Holst, B. (2016). Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a L150P mutation in PSEN-1. Stem Cell Research, 16(1), 110-112. https://doi.org/10.1016/j.scr.2015.12.015

Vancouver

Tubsuwan A, Pires C, Rasmussen MA, Schmid B, Nielsen JE, Hjermind LE o.a. Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a L150P mutation in PSEN-1. Stem Cell Research. 2016 jan.;16(1):110-112. https://doi.org/10.1016/j.scr.2015.12.015

Author

Tubsuwan, Alisa ; Pires, Carlota ; Rasmussen, Mikkel A. ; Schmid, Benjamin ; Nielsen, Jørgen Erik ; Hjermind, Lena Elisabeth ; Hall, Vanessa Jane ; Nielsen, Troels Tolstrup ; Waldemar, Gunhild ; Hyttel, Poul ; Clausen, Christian ; Kitiyanant, Narisorn ; Freude, Kristine ; Holst, Bjørn. / Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a L150P mutation in PSEN-1. I: Stem Cell Research. 2016 ; Bind 16, Nr. 1. s. 110-112.

Bibtex

@article{4e297d9586244cca9e1590acfa4f980b,
title = "Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a L150P mutation in PSEN-1",
abstract = "Induced pluripotent stem cells (iPSCs) were generated from skin fibroblasts isolated from a 58-year old male with a L150P mutation in the presenilin 1 (PSEN-1) gene, which is responsible for the majority of familial cases of Alzheimer's disease (AD). The iPSC swere established by co-electroporation with episomal plasmids containing hOCT4, hSOX2, hL-MYC, hKLF4, hNANOG, hLIN28, and short hairpin RNA against TP53. The iPSCs contained the specific heterozygous mutation c.449C>T, had normal karyotype, expressed the expected pluripotency genes and displayed in vitro differentiation potential to the three germ layers. The iPSCsmay be useful for studying familialAD pathology in vitro.",
author = "Alisa Tubsuwan and Carlota Pires and Rasmussen, {Mikkel A.} and Benjamin Schmid and Nielsen, {J{\o}rgen Erik} and Hjermind, {Lena Elisabeth} and Hall, {Vanessa Jane} and Nielsen, {Troels Tolstrup} and Gunhild Waldemar and Poul Hyttel and Christian Clausen and Narisorn Kitiyanant and Kristine Freude and Bj{\o}rn Holst",
year = "2016",
month = jan,
doi = "10.1016/j.scr.2015.12.015",
language = "English",
volume = "16",
pages = "110--112",
journal = "Stem Cell Research",
issn = "1873-5061",
publisher = "Elsevier",
number = "1",

}

RIS

TY - JOUR

T1 - Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a L150P mutation in PSEN-1

AU - Tubsuwan, Alisa

AU - Pires, Carlota

AU - Rasmussen, Mikkel A.

AU - Schmid, Benjamin

AU - Nielsen, Jørgen Erik

AU - Hjermind, Lena Elisabeth

AU - Hall, Vanessa Jane

AU - Nielsen, Troels Tolstrup

AU - Waldemar, Gunhild

AU - Hyttel, Poul

AU - Clausen, Christian

AU - Kitiyanant, Narisorn

AU - Freude, Kristine

AU - Holst, Bjørn

PY - 2016/1

Y1 - 2016/1

N2 - Induced pluripotent stem cells (iPSCs) were generated from skin fibroblasts isolated from a 58-year old male with a L150P mutation in the presenilin 1 (PSEN-1) gene, which is responsible for the majority of familial cases of Alzheimer's disease (AD). The iPSC swere established by co-electroporation with episomal plasmids containing hOCT4, hSOX2, hL-MYC, hKLF4, hNANOG, hLIN28, and short hairpin RNA against TP53. The iPSCs contained the specific heterozygous mutation c.449C>T, had normal karyotype, expressed the expected pluripotency genes and displayed in vitro differentiation potential to the three germ layers. The iPSCsmay be useful for studying familialAD pathology in vitro.

AB - Induced pluripotent stem cells (iPSCs) were generated from skin fibroblasts isolated from a 58-year old male with a L150P mutation in the presenilin 1 (PSEN-1) gene, which is responsible for the majority of familial cases of Alzheimer's disease (AD). The iPSC swere established by co-electroporation with episomal plasmids containing hOCT4, hSOX2, hL-MYC, hKLF4, hNANOG, hLIN28, and short hairpin RNA against TP53. The iPSCs contained the specific heterozygous mutation c.449C>T, had normal karyotype, expressed the expected pluripotency genes and displayed in vitro differentiation potential to the three germ layers. The iPSCsmay be useful for studying familialAD pathology in vitro.

U2 - 10.1016/j.scr.2015.12.015

DO - 10.1016/j.scr.2015.12.015

M3 - Journal article

C2 - 27345792

VL - 16

SP - 110

EP - 112

JO - Stem Cell Research

JF - Stem Cell Research

SN - 1873-5061

IS - 1

ER -

ID: 162605874