Generation of spinocerebellar ataxia type 2 patient-derived iPSC line H266

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Standard

Generation of spinocerebellar ataxia type 2 patient-derived iPSC line H266. / Marthaler, Adele Gabriele; Schmid, Benjamin; Tubsuwan, Alisa; Poulsen, Ulla B.; Hyttel, Poul; Nielsen, Troels Tolstrup; Nielsen, Jørgen Erik; Holst, Bjørn.

I: Stem Cell Research, Bind 16, Nr. 1, 01.2016, s. 166-169.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Marthaler, AG, Schmid, B, Tubsuwan, A, Poulsen, UB, Hyttel, P, Nielsen, TT, Nielsen, JE & Holst, B 2016, 'Generation of spinocerebellar ataxia type 2 patient-derived iPSC line H266', Stem Cell Research, bind 16, nr. 1, s. 166-169. https://doi.org/10.1016/j.scr.2015.12.029

APA

Marthaler, A. G., Schmid, B., Tubsuwan, A., Poulsen, U. B., Hyttel, P., Nielsen, T. T., Nielsen, J. E., & Holst, B. (2016). Generation of spinocerebellar ataxia type 2 patient-derived iPSC line H266. Stem Cell Research, 16(1), 166-169. https://doi.org/10.1016/j.scr.2015.12.029

Vancouver

Marthaler AG, Schmid B, Tubsuwan A, Poulsen UB, Hyttel P, Nielsen TT o.a. Generation of spinocerebellar ataxia type 2 patient-derived iPSC line H266. Stem Cell Research. 2016 jan.;16(1):166-169. https://doi.org/10.1016/j.scr.2015.12.029

Author

Marthaler, Adele Gabriele ; Schmid, Benjamin ; Tubsuwan, Alisa ; Poulsen, Ulla B. ; Hyttel, Poul ; Nielsen, Troels Tolstrup ; Nielsen, Jørgen Erik ; Holst, Bjørn. / Generation of spinocerebellar ataxia type 2 patient-derived iPSC line H266. I: Stem Cell Research. 2016 ; Bind 16, Nr. 1. s. 166-169.

Bibtex

@article{41b0c587add548e88eaa9b5441cbb607,
title = "Generation of spinocerebellar ataxia type 2 patient-derived iPSC line H266",
abstract = "Spinocerebellar ataxia type 2 (SCA2) is a neurodegenerative disease primarily affecting the cerebellum. Very little is known about the molecular mechanisms underlying the disease and, to date, no cure or treatment is available. Here, we demonstrate the generation of an induced pluripotent stem cell (iPSC) line of a SCA2 patient. The selected clone has been proven to be a bona fide iPSC line, which retains a normal karyotype. Due to its differentiation potential into neurons, this iPSC line will be a valuable tool in studying a disease-specific phenotype of SCA2.",
keywords = "Alleles, Ataxin-2, Base Sequence, Cell Differentiation, Cell Line, Cellular Reprogramming, Humans, Induced Pluripotent Stem Cells, Karyotype, Male, Molecular Sequence Data, Plasmids, Sequence Analysis, DNA, Spinocerebellar Ataxias, Transcription Factors, Transfection, Journal Article, Research Support, Non-U.S. Gov't",
author = "Marthaler, {Adele Gabriele} and Benjamin Schmid and Alisa Tubsuwan and Poulsen, {Ulla B.} and Poul Hyttel and Nielsen, {Troels Tolstrup} and Nielsen, {J{\o}rgen Erik} and Bj{\o}rn Holst",
note = "Copyright {\textcopyright} 2016. Published by Elsevier B.V.",
year = "2016",
month = jan,
doi = "10.1016/j.scr.2015.12.029",
language = "English",
volume = "16",
pages = "166--169",
journal = "Stem Cell Research",
issn = "1873-5061",
publisher = "Elsevier",
number = "1",

}

RIS

TY - JOUR

T1 - Generation of spinocerebellar ataxia type 2 patient-derived iPSC line H266

AU - Marthaler, Adele Gabriele

AU - Schmid, Benjamin

AU - Tubsuwan, Alisa

AU - Poulsen, Ulla B.

AU - Hyttel, Poul

AU - Nielsen, Troels Tolstrup

AU - Nielsen, Jørgen Erik

AU - Holst, Bjørn

N1 - Copyright © 2016. Published by Elsevier B.V.

PY - 2016/1

Y1 - 2016/1

N2 - Spinocerebellar ataxia type 2 (SCA2) is a neurodegenerative disease primarily affecting the cerebellum. Very little is known about the molecular mechanisms underlying the disease and, to date, no cure or treatment is available. Here, we demonstrate the generation of an induced pluripotent stem cell (iPSC) line of a SCA2 patient. The selected clone has been proven to be a bona fide iPSC line, which retains a normal karyotype. Due to its differentiation potential into neurons, this iPSC line will be a valuable tool in studying a disease-specific phenotype of SCA2.

AB - Spinocerebellar ataxia type 2 (SCA2) is a neurodegenerative disease primarily affecting the cerebellum. Very little is known about the molecular mechanisms underlying the disease and, to date, no cure or treatment is available. Here, we demonstrate the generation of an induced pluripotent stem cell (iPSC) line of a SCA2 patient. The selected clone has been proven to be a bona fide iPSC line, which retains a normal karyotype. Due to its differentiation potential into neurons, this iPSC line will be a valuable tool in studying a disease-specific phenotype of SCA2.

KW - Alleles

KW - Ataxin-2

KW - Base Sequence

KW - Cell Differentiation

KW - Cell Line

KW - Cellular Reprogramming

KW - Humans

KW - Induced Pluripotent Stem Cells

KW - Karyotype

KW - Male

KW - Molecular Sequence Data

KW - Plasmids

KW - Sequence Analysis, DNA

KW - Spinocerebellar Ataxias

KW - Transcription Factors

KW - Transfection

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

U2 - 10.1016/j.scr.2015.12.029

DO - 10.1016/j.scr.2015.12.029

M3 - Journal article

C2 - 27345805

VL - 16

SP - 166

EP - 169

JO - Stem Cell Research

JF - Stem Cell Research

SN - 1873-5061

IS - 1

ER -

ID: 172821288