Impaired performances on the category cued memory test in mild Alzheimer’s disease and dementia with Lewy bodies: A comparative validity study
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Impaired performances on the category cued memory test in mild Alzheimer’s disease and dementia with Lewy bodies : A comparative validity study. / Vogel, Asmus; Mellergaard, Clara; Waldemar, Gunhild; Frederiksen, Kristian Steen.
I: Applied Neuropsychology:Adult, 2024.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Impaired performances on the category cued memory test in mild Alzheimer’s disease and dementia with Lewy bodies
T2 - A comparative validity study
AU - Vogel, Asmus
AU - Mellergaard, Clara
AU - Waldemar, Gunhild
AU - Frederiksen, Kristian Steen
N1 - Publisher Copyright: © 2021 Taylor & Francis Group, LLC.
PY - 2024
Y1 - 2024
N2 - Cued recall taps amnesia of “the hippocampal type” as typically found in Alzheimer’s disease (AD). Studies investigating the validity of cued recall measures in AD have typically been conducted in research settings. The Category Cued Memory Test (CCMT-48) measures learning/memory using the same categories during encoding and acquisition. The aim of this study was to investigate how frequently impairments were found on the CCMT-48 mild AD patients from a memory clinic (N = 77). We used a case-oriented approach where individually observed scores were compared to expected scores derived from regressions-based normative data. We also investigated if CCMT-48 performances differed in patients with mild AD and Dementia with Lewy Bodies (DLB) (N = 90). The results showed a significantly higher frequency of impairment in the AD group as compared to the DLB group for scores below 10th percentile-estimate (impaired: AD 88%; DLB 69%) and 5th percentile-estimate (impaired: AD 82%; DLB 53%). In conclusion, a very high frequency of impairment of a picture-based cued recall test in AD patients (very high sensitivity) in a memory clinic setting. However, specificity is not optimal since impairments also frequently occurred in DLB where memory problems could be assumed to be part of attentional deficits and poor retrieval strategies.
AB - Cued recall taps amnesia of “the hippocampal type” as typically found in Alzheimer’s disease (AD). Studies investigating the validity of cued recall measures in AD have typically been conducted in research settings. The Category Cued Memory Test (CCMT-48) measures learning/memory using the same categories during encoding and acquisition. The aim of this study was to investigate how frequently impairments were found on the CCMT-48 mild AD patients from a memory clinic (N = 77). We used a case-oriented approach where individually observed scores were compared to expected scores derived from regressions-based normative data. We also investigated if CCMT-48 performances differed in patients with mild AD and Dementia with Lewy Bodies (DLB) (N = 90). The results showed a significantly higher frequency of impairment in the AD group as compared to the DLB group for scores below 10th percentile-estimate (impaired: AD 88%; DLB 69%) and 5th percentile-estimate (impaired: AD 82%; DLB 53%). In conclusion, a very high frequency of impairment of a picture-based cued recall test in AD patients (very high sensitivity) in a memory clinic setting. However, specificity is not optimal since impairments also frequently occurred in DLB where memory problems could be assumed to be part of attentional deficits and poor retrieval strategies.
KW - Alzheimer’s disease
KW - cued recall
KW - dementia
KW - Lewy body
KW - memory
U2 - 10.1080/23279095.2021.2021413
DO - 10.1080/23279095.2021.2021413
M3 - Journal article
C2 - 34958289
AN - SCOPUS:85121857860
JO - Applied neuropsychology. Adult
JF - Applied neuropsychology. Adult
SN - 2327-9095
ER -
ID: 290254140