Induced pluripotent stem cells (iPSCs) derived from a patient with frontotemporal dementia caused by a P301L mutation in microtubule-associated protein tau (MAPT)

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Standard

Induced pluripotent stem cells (iPSCs) derived from a patient with frontotemporal dementia caused by a P301L mutation in microtubule-associated protein tau (MAPT). / Rasmussen, Mikkel A.; Hjermind, Lena Elisabeth; Hasholt, Lis Frydenreich; Waldemar, Gunhild; Nielsen, Jørgen Erik; Clausen, Christian; Hyttel, Poul; Holst, Bjørn.

I: Stem Cell Research, Bind 16, Nr. 1, 2016, s. 70-74.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Rasmussen, MA, Hjermind, LE, Hasholt, LF, Waldemar, G, Nielsen, JE, Clausen, C, Hyttel, P & Holst, B 2016, 'Induced pluripotent stem cells (iPSCs) derived from a patient with frontotemporal dementia caused by a P301L mutation in microtubule-associated protein tau (MAPT)', Stem Cell Research, bind 16, nr. 1, s. 70-74. https://doi.org/10.1016/j.scr.2015.12.008

APA

Rasmussen, M. A., Hjermind, L. E., Hasholt, L. F., Waldemar, G., Nielsen, J. E., Clausen, C., Hyttel, P., & Holst, B. (2016). Induced pluripotent stem cells (iPSCs) derived from a patient with frontotemporal dementia caused by a P301L mutation in microtubule-associated protein tau (MAPT). Stem Cell Research, 16(1), 70-74. https://doi.org/10.1016/j.scr.2015.12.008

Vancouver

Rasmussen MA, Hjermind LE, Hasholt LF, Waldemar G, Nielsen JE, Clausen C o.a. Induced pluripotent stem cells (iPSCs) derived from a patient with frontotemporal dementia caused by a P301L mutation in microtubule-associated protein tau (MAPT). Stem Cell Research. 2016;16(1):70-74. https://doi.org/10.1016/j.scr.2015.12.008

Author

Rasmussen, Mikkel A. ; Hjermind, Lena Elisabeth ; Hasholt, Lis Frydenreich ; Waldemar, Gunhild ; Nielsen, Jørgen Erik ; Clausen, Christian ; Hyttel, Poul ; Holst, Bjørn. / Induced pluripotent stem cells (iPSCs) derived from a patient with frontotemporal dementia caused by a P301L mutation in microtubule-associated protein tau (MAPT). I: Stem Cell Research. 2016 ; Bind 16, Nr. 1. s. 70-74.

Bibtex

@article{49b1fcf320ec4b5b8e0c917868e14e1c,
title = "Induced pluripotent stem cells (iPSCs) derived from a patient with frontotemporal dementia caused by a P301L mutation in microtubule-associated protein tau (MAPT)",
abstract = "Skin fibroblasts were obtained froma 57-year-old woman diagnosed with frontotemporal dementia. The diseaseis caused by a P301L mutation in microtubule-associated protein tau (MAPT). Induced pluripotent stem cells (iPSCs) were established by electroporation with episomal plasmids containing hOCT4, hSOX2, hKLF2, hL-MYC,hLIN-28 and shP53. iPSCs were free of genomically integrated reprogramming genes, contained the expected c.902C>T substitution in exon 10 of the MAPT gene, expressed the expected pluripotency markers, displayed in vitro differentiation potential to the three germ layers and had normal karyotype. The iPSC line may be useful for studying hereditary frontotemporal dementia and TAU pathology in vitro.",
author = "Rasmussen, {Mikkel A.} and Hjermind, {Lena Elisabeth} and Hasholt, {Lis Frydenreich} and Gunhild Waldemar and Nielsen, {J{\o}rgen Erik} and Christian Clausen and Poul Hyttel and Bj{\o}rn Holst",
year = "2016",
doi = "10.1016/j.scr.2015.12.008",
language = "English",
volume = "16",
pages = "70--74",
journal = "Stem Cell Research",
issn = "1873-5061",
publisher = "Elsevier",
number = "1",

}

RIS

TY - JOUR

T1 - Induced pluripotent stem cells (iPSCs) derived from a patient with frontotemporal dementia caused by a P301L mutation in microtubule-associated protein tau (MAPT)

AU - Rasmussen, Mikkel A.

AU - Hjermind, Lena Elisabeth

AU - Hasholt, Lis Frydenreich

AU - Waldemar, Gunhild

AU - Nielsen, Jørgen Erik

AU - Clausen, Christian

AU - Hyttel, Poul

AU - Holst, Bjørn

PY - 2016

Y1 - 2016

N2 - Skin fibroblasts were obtained froma 57-year-old woman diagnosed with frontotemporal dementia. The diseaseis caused by a P301L mutation in microtubule-associated protein tau (MAPT). Induced pluripotent stem cells (iPSCs) were established by electroporation with episomal plasmids containing hOCT4, hSOX2, hKLF2, hL-MYC,hLIN-28 and shP53. iPSCs were free of genomically integrated reprogramming genes, contained the expected c.902C>T substitution in exon 10 of the MAPT gene, expressed the expected pluripotency markers, displayed in vitro differentiation potential to the three germ layers and had normal karyotype. The iPSC line may be useful for studying hereditary frontotemporal dementia and TAU pathology in vitro.

AB - Skin fibroblasts were obtained froma 57-year-old woman diagnosed with frontotemporal dementia. The diseaseis caused by a P301L mutation in microtubule-associated protein tau (MAPT). Induced pluripotent stem cells (iPSCs) were established by electroporation with episomal plasmids containing hOCT4, hSOX2, hKLF2, hL-MYC,hLIN-28 and shP53. iPSCs were free of genomically integrated reprogramming genes, contained the expected c.902C>T substitution in exon 10 of the MAPT gene, expressed the expected pluripotency markers, displayed in vitro differentiation potential to the three germ layers and had normal karyotype. The iPSC line may be useful for studying hereditary frontotemporal dementia and TAU pathology in vitro.

U2 - 10.1016/j.scr.2015.12.008

DO - 10.1016/j.scr.2015.12.008

M3 - Journal article

C2 - 27345788

VL - 16

SP - 70

EP - 74

JO - Stem Cell Research

JF - Stem Cell Research

SN - 1873-5061

IS - 1

ER -

ID: 162605940