Regional cerebral blood flow and neuropsychological performance in a Danish family with X-linked bulbo-spinal neuronopathy

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Standard

Regional cerebral blood flow and neuropsychological performance in a Danish family with X-linked bulbo-spinal neuronopathy. / Tedeschi, E; Waldemar, G; Gyring, J; Gade, A; Staehelin Jensen, T; Paulson, O B.

I: International Journal of Neuroscience, Bind 83, Nr. 1-2, 11.1995, s. 59-68.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Tedeschi, E, Waldemar, G, Gyring, J, Gade, A, Staehelin Jensen, T & Paulson, OB 1995, 'Regional cerebral blood flow and neuropsychological performance in a Danish family with X-linked bulbo-spinal neuronopathy', International Journal of Neuroscience, bind 83, nr. 1-2, s. 59-68. https://doi.org/10.3109/00207459508986325

APA

Tedeschi, E., Waldemar, G., Gyring, J., Gade, A., Staehelin Jensen, T., & Paulson, O. B. (1995). Regional cerebral blood flow and neuropsychological performance in a Danish family with X-linked bulbo-spinal neuronopathy. International Journal of Neuroscience, 83(1-2), 59-68. https://doi.org/10.3109/00207459508986325

Vancouver

Tedeschi E, Waldemar G, Gyring J, Gade A, Staehelin Jensen T, Paulson OB. Regional cerebral blood flow and neuropsychological performance in a Danish family with X-linked bulbo-spinal neuronopathy. International Journal of Neuroscience. 1995 nov.;83(1-2):59-68. https://doi.org/10.3109/00207459508986325

Author

Tedeschi, E ; Waldemar, G ; Gyring, J ; Gade, A ; Staehelin Jensen, T ; Paulson, O B. / Regional cerebral blood flow and neuropsychological performance in a Danish family with X-linked bulbo-spinal neuronopathy. I: International Journal of Neuroscience. 1995 ; Bind 83, Nr. 1-2. s. 59-68.

Bibtex

@article{b060086810474a1ab2dad55a766677b4,
title = "Regional cerebral blood flow and neuropsychological performance in a Danish family with X-linked bulbo-spinal neuronopathy",
abstract = "Regional Cerebral Blood Flow (rCBF) measurements and neuropsychological evaluation were performed in 6 patients from a Danish family affected with X-linked Bulbo-Spinal Neuronopathy (XBSN). This inherited form of motor neuron disease (MND) has been shown to affect various functions within the nervous and the endocrine systems. We investigated the possibility that focal or diffuse cortical deficits, already demonstrated in MND, were present in XBSN. The global CBF values of the patients, when compared to age- and sex-matched healthy controls, were found reduced, but no focal rCBF alterations, nor increased regional side-to-side asymmetry were observed. The neuropsychological evaluation showed no cognitive impairments. We conclude that cortical perfusion and cognitive functions are not significantly altered in XBSN.",
keywords = "Adult, Brain/blood supply, Denmark, Female, Humans, Male, Middle Aged, Motor Neuron Disease/diagnosis, Neuropsychological Tests, Pedigree, Regional Blood Flow, Tomography, Emission-Computed, Single-Photon, Tomography, X-Ray Computed, X Chromosome",
author = "E Tedeschi and G Waldemar and J Gyring and A Gade and {Staehelin Jensen}, T and Paulson, {O B}",
year = "1995",
month = nov,
doi = "10.3109/00207459508986325",
language = "English",
volume = "83",
pages = "59--68",
journal = "International Journal of Neuroscience",
issn = "0020-7454",
publisher = "Taylor & Francis",
number = "1-2",

}

RIS

TY - JOUR

T1 - Regional cerebral blood flow and neuropsychological performance in a Danish family with X-linked bulbo-spinal neuronopathy

AU - Tedeschi, E

AU - Waldemar, G

AU - Gyring, J

AU - Gade, A

AU - Staehelin Jensen, T

AU - Paulson, O B

PY - 1995/11

Y1 - 1995/11

N2 - Regional Cerebral Blood Flow (rCBF) measurements and neuropsychological evaluation were performed in 6 patients from a Danish family affected with X-linked Bulbo-Spinal Neuronopathy (XBSN). This inherited form of motor neuron disease (MND) has been shown to affect various functions within the nervous and the endocrine systems. We investigated the possibility that focal or diffuse cortical deficits, already demonstrated in MND, were present in XBSN. The global CBF values of the patients, when compared to age- and sex-matched healthy controls, were found reduced, but no focal rCBF alterations, nor increased regional side-to-side asymmetry were observed. The neuropsychological evaluation showed no cognitive impairments. We conclude that cortical perfusion and cognitive functions are not significantly altered in XBSN.

AB - Regional Cerebral Blood Flow (rCBF) measurements and neuropsychological evaluation were performed in 6 patients from a Danish family affected with X-linked Bulbo-Spinal Neuronopathy (XBSN). This inherited form of motor neuron disease (MND) has been shown to affect various functions within the nervous and the endocrine systems. We investigated the possibility that focal or diffuse cortical deficits, already demonstrated in MND, were present in XBSN. The global CBF values of the patients, when compared to age- and sex-matched healthy controls, were found reduced, but no focal rCBF alterations, nor increased regional side-to-side asymmetry were observed. The neuropsychological evaluation showed no cognitive impairments. We conclude that cortical perfusion and cognitive functions are not significantly altered in XBSN.

KW - Adult

KW - Brain/blood supply

KW - Denmark

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Motor Neuron Disease/diagnosis

KW - Neuropsychological Tests

KW - Pedigree

KW - Regional Blood Flow

KW - Tomography, Emission-Computed, Single-Photon

KW - Tomography, X-Ray Computed

KW - X Chromosome

U2 - 10.3109/00207459508986325

DO - 10.3109/00207459508986325

M3 - Journal article

C2 - 8746749

VL - 83

SP - 59

EP - 68

JO - International Journal of Neuroscience

JF - International Journal of Neuroscience

SN - 0020-7454

IS - 1-2

ER -

ID: 275018132