Role of the local renin-angiotensin system in the autoregulation of the cerebral circulation

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Standard

Role of the local renin-angiotensin system in the autoregulation of the cerebral circulation. / Paulson, O B; Waldemar, G.

I: Blood Vessels, Bind 28, Nr. 1-3, 1991, s. 231-5.

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Harvard

Paulson, OB & Waldemar, G 1991, 'Role of the local renin-angiotensin system in the autoregulation of the cerebral circulation', Blood Vessels, bind 28, nr. 1-3, s. 231-5. https://doi.org/10.1159/000158867

APA

Paulson, O. B., & Waldemar, G. (1991). Role of the local renin-angiotensin system in the autoregulation of the cerebral circulation. Blood Vessels, 28(1-3), 231-5. https://doi.org/10.1159/000158867

Vancouver

Paulson OB, Waldemar G. Role of the local renin-angiotensin system in the autoregulation of the cerebral circulation. Blood Vessels. 1991;28(1-3):231-5. https://doi.org/10.1159/000158867

Author

Paulson, O B ; Waldemar, G. / Role of the local renin-angiotensin system in the autoregulation of the cerebral circulation. I: Blood Vessels. 1991 ; Bind 28, Nr. 1-3. s. 231-5.

Bibtex

@article{df4afc19c75d4e668daa70960d855dfb,
title = "Role of the local renin-angiotensin system in the autoregulation of the cerebral circulation",
abstract = "Inhibition of angiotensin-converting enzyme (ACE) shifts the limits of cerebral blood flow autoregulation toward lower blood pressure values. This effect seems to be mediated by blocking the formation of angiotensin II on the luminal side of the larger cerebral resistance vessels. Baseline cerebral blood flow (the flow within the autoregulatory limits) is not changed by acute or chronic ACE inhibition. An interaction between the vascular reninangiotensin and the sympathetic nervous system is present. Activation of the latter inhibits the downwards shift of the upper limit of autoregulation following ACE inhibition.",
keywords = "Angiotensin-Converting Enzyme Inhibitors/pharmacology, Animals, Cerebral Arteries/enzymology, Cerebrovascular Circulation/drug effects, Homeostasis, Humans, Renin-Angiotensin System/physiology, Sympathetic Nervous System/physiology",
author = "Paulson, {O B} and G Waldemar",
year = "1991",
doi = "10.1159/000158867",
language = "English",
volume = "28",
pages = "231--5",
journal = "Blood Vessels",
issn = "0303-6847",
publisher = "Karger",
number = "1-3",

}

RIS

TY - JOUR

T1 - Role of the local renin-angiotensin system in the autoregulation of the cerebral circulation

AU - Paulson, O B

AU - Waldemar, G

PY - 1991

Y1 - 1991

N2 - Inhibition of angiotensin-converting enzyme (ACE) shifts the limits of cerebral blood flow autoregulation toward lower blood pressure values. This effect seems to be mediated by blocking the formation of angiotensin II on the luminal side of the larger cerebral resistance vessels. Baseline cerebral blood flow (the flow within the autoregulatory limits) is not changed by acute or chronic ACE inhibition. An interaction between the vascular reninangiotensin and the sympathetic nervous system is present. Activation of the latter inhibits the downwards shift of the upper limit of autoregulation following ACE inhibition.

AB - Inhibition of angiotensin-converting enzyme (ACE) shifts the limits of cerebral blood flow autoregulation toward lower blood pressure values. This effect seems to be mediated by blocking the formation of angiotensin II on the luminal side of the larger cerebral resistance vessels. Baseline cerebral blood flow (the flow within the autoregulatory limits) is not changed by acute or chronic ACE inhibition. An interaction between the vascular reninangiotensin and the sympathetic nervous system is present. Activation of the latter inhibits the downwards shift of the upper limit of autoregulation following ACE inhibition.

KW - Angiotensin-Converting Enzyme Inhibitors/pharmacology

KW - Animals

KW - Cerebral Arteries/enzymology

KW - Cerebrovascular Circulation/drug effects

KW - Homeostasis

KW - Humans

KW - Renin-Angiotensin System/physiology

KW - Sympathetic Nervous System/physiology

U2 - 10.1159/000158867

DO - 10.1159/000158867

M3 - Review

C2 - 2001474

VL - 28

SP - 231

EP - 235

JO - Blood Vessels

JF - Blood Vessels

SN - 0303-6847

IS - 1-3

ER -

ID: 275017735