The potential of microRNAs as biofluid markers of neurodegenerative diseases – a systematic review

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Standard

The potential of microRNAs as biofluid markers of neurodegenerative diseases – a systematic review. / Danborg, Pia B; Simonsen, Anja H; Waldemar, Gunhild; Heegaard, Niels H H.

I: Biomarkers, Bind 19, Nr. 4, 06.2014, s. 259-268.

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Harvard

Danborg, PB, Simonsen, AH, Waldemar, G & Heegaard, NHH 2014, 'The potential of microRNAs as biofluid markers of neurodegenerative diseases – a systematic review', Biomarkers, bind 19, nr. 4, s. 259-268. https://doi.org/10.3109/1354750X.2014.904001

APA

Danborg, P. B., Simonsen, A. H., Waldemar, G., & Heegaard, N. H. H. (2014). The potential of microRNAs as biofluid markers of neurodegenerative diseases – a systematic review. Biomarkers, 19(4), 259-268. https://doi.org/10.3109/1354750X.2014.904001

Vancouver

Danborg PB, Simonsen AH, Waldemar G, Heegaard NHH. The potential of microRNAs as biofluid markers of neurodegenerative diseases – a systematic review. Biomarkers. 2014 jun.;19(4):259-268. https://doi.org/10.3109/1354750X.2014.904001

Author

Danborg, Pia B ; Simonsen, Anja H ; Waldemar, Gunhild ; Heegaard, Niels H H. / The potential of microRNAs as biofluid markers of neurodegenerative diseases – a systematic review. I: Biomarkers. 2014 ; Bind 19, Nr. 4. s. 259-268.

Bibtex

@article{d83357f4c83a4fb9baef5e5db0932560,
title = "The potential of microRNAs as biofluid markers of neurodegenerative diseases – a systematic review",
abstract = "MicroRNAs (miRNA) are biological molecules transcribed from non-protein coding regions of the genome, participating in regulating cellular processes. MiRNAs in biofluids may possess neurodegenerative disease biomarker potential for screening tests, differential diagnosis and disease progression monitoring. This systematic review clarifies biomarker potential of miRNAs detected in biofluids of neurodegenerative disease patients. Thirty-three and ten miRNAs displayed significant expression between patients with multiple sclerosis and Alzheimer's disease, respectively, compared to healthy controls in minimum two studies. Thirty-eight miRNAs showed biomarker potential by distinguishing significantly between minimum two diseases. Summarized data directs future research towards discovering new biomarkers for neurodegenerative diseases.",
keywords = "Biological Markers, Cognition Disorders, Humans, MicroRNAs, Neurodegenerative Diseases",
author = "Danborg, {Pia B} and Simonsen, {Anja H} and Gunhild Waldemar and Heegaard, {Niels H H}",
year = "2014",
month = jun,
doi = "10.3109/1354750X.2014.904001",
language = "English",
volume = "19",
pages = "259--268",
journal = "Biomarkers",
issn = "1354-750X",
publisher = "Taylor & Francis",
number = "4",

}

RIS

TY - JOUR

T1 - The potential of microRNAs as biofluid markers of neurodegenerative diseases – a systematic review

AU - Danborg, Pia B

AU - Simonsen, Anja H

AU - Waldemar, Gunhild

AU - Heegaard, Niels H H

PY - 2014/6

Y1 - 2014/6

N2 - MicroRNAs (miRNA) are biological molecules transcribed from non-protein coding regions of the genome, participating in regulating cellular processes. MiRNAs in biofluids may possess neurodegenerative disease biomarker potential for screening tests, differential diagnosis and disease progression monitoring. This systematic review clarifies biomarker potential of miRNAs detected in biofluids of neurodegenerative disease patients. Thirty-three and ten miRNAs displayed significant expression between patients with multiple sclerosis and Alzheimer's disease, respectively, compared to healthy controls in minimum two studies. Thirty-eight miRNAs showed biomarker potential by distinguishing significantly between minimum two diseases. Summarized data directs future research towards discovering new biomarkers for neurodegenerative diseases.

AB - MicroRNAs (miRNA) are biological molecules transcribed from non-protein coding regions of the genome, participating in regulating cellular processes. MiRNAs in biofluids may possess neurodegenerative disease biomarker potential for screening tests, differential diagnosis and disease progression monitoring. This systematic review clarifies biomarker potential of miRNAs detected in biofluids of neurodegenerative disease patients. Thirty-three and ten miRNAs displayed significant expression between patients with multiple sclerosis and Alzheimer's disease, respectively, compared to healthy controls in minimum two studies. Thirty-eight miRNAs showed biomarker potential by distinguishing significantly between minimum two diseases. Summarized data directs future research towards discovering new biomarkers for neurodegenerative diseases.

KW - Biological Markers

KW - Cognition Disorders

KW - Humans

KW - MicroRNAs

KW - Neurodegenerative Diseases

U2 - 10.3109/1354750X.2014.904001

DO - 10.3109/1354750X.2014.904001

M3 - Review

C2 - 24678935

VL - 19

SP - 259

EP - 268

JO - Biomarkers

JF - Biomarkers

SN - 1354-750X

IS - 4

ER -

ID: 138620316