The six-item Clock Drawing Test – reliability and validity in mild Alzheimer’s disease
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The six-item Clock Drawing Test – reliability and validity in mild Alzheimer’s disease. / Jørgensen, Kasper; Kristensen, Maria K; Waldemar, Gunhild; Vogel, Asmus.
I: Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition, Bind 22, Nr. 3, 2015, s. 301-311.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - The six-item Clock Drawing Test – reliability and validity in mild Alzheimer’s disease
AU - Jørgensen, Kasper
AU - Kristensen, Maria K
AU - Waldemar, Gunhild
AU - Vogel, Asmus
PY - 2015
Y1 - 2015
N2 - This study presents a reliable, short and practical version of the Clock Drawing Test (CDT) for clinical use and examines its diagnostic accuracy in mild Alzheimer's disease versus elderly nonpatients. Clock drawings from 231 participants were scored independently by four clinical neuropsychologists blind to diagnostic classification. The interrater agreement of individual scoring criteria was analyzed and items with poor or moderate reliability were excluded. The classification accuracy of the resulting scoring system - the six-item CDT - was examined. We explored the effect of further reducing the number of scoring items on classification accuracy and estimated classification accuracy associated with performances deviating from the optimal cutoff score. At a cutoff of 5/6, the six-item CDT had a sensitivity (SN) of 0.65 and a specificity of 0.80. Stepwise removal of up to three items reduced SN slightly. Classification accuracy associated with a score of four or less out of six was very high.
AB - This study presents a reliable, short and practical version of the Clock Drawing Test (CDT) for clinical use and examines its diagnostic accuracy in mild Alzheimer's disease versus elderly nonpatients. Clock drawings from 231 participants were scored independently by four clinical neuropsychologists blind to diagnostic classification. The interrater agreement of individual scoring criteria was analyzed and items with poor or moderate reliability were excluded. The classification accuracy of the resulting scoring system - the six-item CDT - was examined. We explored the effect of further reducing the number of scoring items on classification accuracy and estimated classification accuracy associated with performances deviating from the optimal cutoff score. At a cutoff of 5/6, the six-item CDT had a sensitivity (SN) of 0.65 and a specificity of 0.80. Stepwise removal of up to three items reduced SN slightly. Classification accuracy associated with a score of four or less out of six was very high.
KW - Aged
KW - Aged, 80 and over
KW - Alzheimer Disease
KW - Female
KW - Geriatric Assessment
KW - Humans
KW - Male
KW - Neuropsychological Tests
KW - Psychiatric Status Rating Scales
KW - ROC Curve
KW - Reproducibility of Results
KW - Severity of Illness Index
U2 - 10.1080/13825585.2014.932325
DO - 10.1080/13825585.2014.932325
M3 - Journal article
C2 - 24974730
VL - 22
SP - 301
EP - 311
JO - Aging, Neuropsychology, and Cognition
JF - Aging, Neuropsychology, and Cognition
SN - 1382-5585
IS - 3
ER -
ID: 152246267