Torben Fog – A Danish pioneer in a multi-faceted spectrum of multiple sclerosis research
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Torben Fog – A Danish pioneer in a multi-faceted spectrum of multiple sclerosis research. / Sørensen, Per Soelberg; Bramow, Stephan; Magyari, Melinda; Werdelin, Lene; Koch-Henriksen, Nils; Vermersch, Patrick; Sellebjerg, Finn.
I: Multiple Sclerosis Journal, 2024.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Torben Fog – A Danish pioneer in a multi-faceted spectrum of multiple sclerosis research
AU - Sørensen, Per Soelberg
AU - Bramow, Stephan
AU - Magyari, Melinda
AU - Werdelin, Lene
AU - Koch-Henriksen, Nils
AU - Vermersch, Patrick
AU - Sellebjerg, Finn
N1 - Publisher Copyright: © The Author(s), 2024.
PY - 2024
Y1 - 2024
N2 - Torben Fog was committed to multiple sclerosis (MS) research for more than four decades, starting before the defence of his thesis in 1948 and lasting until his death in 1987. His research was multi-facetted, making him one of the great pioneers in the study of essential parts of the pathology, immunology and treatment of MS. He has contributed with meticulous studies of the MS plaques, documenting the perivenous distribution of plaques in the spinal cord. He constructed a scoring system for the disability in MS and used a computer programme to calculate a total neurological deficit. Together with his co-workers, Fog in 1972 was the first to report the association between MS and the human leukocyte antigen system. Fog can be considered as the father of immunomodulatory therapy in MS, treating MS patients with the first transfer factor, and as early as 1980, he was the first to treat MS with intramuscular natural interferon.
AB - Torben Fog was committed to multiple sclerosis (MS) research for more than four decades, starting before the defence of his thesis in 1948 and lasting until his death in 1987. His research was multi-facetted, making him one of the great pioneers in the study of essential parts of the pathology, immunology and treatment of MS. He has contributed with meticulous studies of the MS plaques, documenting the perivenous distribution of plaques in the spinal cord. He constructed a scoring system for the disability in MS and used a computer programme to calculate a total neurological deficit. Together with his co-workers, Fog in 1972 was the first to report the association between MS and the human leukocyte antigen system. Fog can be considered as the father of immunomodulatory therapy in MS, treating MS patients with the first transfer factor, and as early as 1980, he was the first to treat MS with intramuscular natural interferon.
KW - clinical trial
KW - disease modifying therapies
KW - Multiple sclerosis
KW - multiple sclerosis pathology
U2 - 10.1177/13524585241239506
DO - 10.1177/13524585241239506
M3 - Journal article
C2 - 38523325
AN - SCOPUS:85189134204
JO - Multiple Sclerosis Journal
JF - Multiple Sclerosis Journal
SN - 1352-4585
ER -
ID: 388016337