99mTc-DPD uptake in juvenile hemarthrosis. Scintimetry and autoradiography of the knee in dogs

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Standard

99mTc-DPD uptake in juvenile hemarthrosis. Scintimetry and autoradiography of the knee in dogs. / Hansen, E S; Hjortdal, V E; Noer, I; Christensen, S B; Holm, I E; Bünger, C.

I: Orthopedics, Bind 12, Nr. 3, 03.1989, s. 441-7.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Hansen, ES, Hjortdal, VE, Noer, I, Christensen, SB, Holm, IE & Bünger, C 1989, '99mTc-DPD uptake in juvenile hemarthrosis. Scintimetry and autoradiography of the knee in dogs', Orthopedics, bind 12, nr. 3, s. 441-7.

APA

Hansen, E. S., Hjortdal, V. E., Noer, I., Christensen, S. B., Holm, I. E., & Bünger, C. (1989). 99mTc-DPD uptake in juvenile hemarthrosis. Scintimetry and autoradiography of the knee in dogs. Orthopedics, 12(3), 441-7.

Vancouver

Hansen ES, Hjortdal VE, Noer I, Christensen SB, Holm IE, Bünger C. 99mTc-DPD uptake in juvenile hemarthrosis. Scintimetry and autoradiography of the knee in dogs. Orthopedics. 1989 mar.;12(3):441-7.

Author

Hansen, E S ; Hjortdal, V E ; Noer, I ; Christensen, S B ; Holm, I E ; Bünger, C. / 99mTc-DPD uptake in juvenile hemarthrosis. Scintimetry and autoradiography of the knee in dogs. I: Orthopedics. 1989 ; Bind 12, Nr. 3. s. 441-7.

Bibtex

@article{a5c40af10f8e4e84a54c43a79bc7d7bd,
title = "99mTc-DPD uptake in juvenile hemarthrosis. Scintimetry and autoradiography of the knee in dogs",
abstract = "The pathogenesis of subchondral bone lesions and growth plate affection in hemophilic arthropathy was studied in puppies by means of repeated regional 99mTc-diphosphonate scintimetry and contact autoradiography. Unilateral hemarthrosis of the knee was induced by biweekly intraarticular injections of autologous blood for 12 weeks. Hemarthrosis caused an early (2 to 4 weeks) decrease in uptake of 99mTc-diphosphonate in the juxtaarticular growth plates (ratio 0.7) and a delayed (8 to 10 weeks) increase in epiphyseal uptake (ratio 1.5). In a recovery phase after hemarthrosis, growth plate uptake returned to normal, while the epiphyseal uptake remained elevated for 8 to 10 weeks. By contact autoradiography, the growth plate uptake was localized to the calcification layer at the metaphyseal aspect of the growth plates, while the epiphyseal uptake mainly was seen in the thin subchondral and subsynovial bone layer and around osteophytes. The changes in uptake of 99mTc-diphosphonate following hemarthrosis for 3 months were reversible and could be ascribed to the presence of synovial inflammation.",
keywords = "Animals, Autoradiography, Child, Diphosphonates, Disease Models, Animal, Dogs, Growth Plate/diagnostic imaging, Hemarthrosis/diagnostic imaging, Humans, Knee Joint/blood supply, Organometallic Compounds, Organotechnetium Compounds, Radiography, Radionuclide Imaging",
author = "Hansen, {E S} and Hjortdal, {V E} and I Noer and Christensen, {S B} and Holm, {I E} and C B{\"u}nger",
year = "1989",
month = mar,
language = "English",
volume = "12",
pages = "441--7",
journal = "Orthopedics",
issn = "0147-7447",
publisher = "Slack, Inc.",
number = "3",

}

RIS

TY - JOUR

T1 - 99mTc-DPD uptake in juvenile hemarthrosis. Scintimetry and autoradiography of the knee in dogs

AU - Hansen, E S

AU - Hjortdal, V E

AU - Noer, I

AU - Christensen, S B

AU - Holm, I E

AU - Bünger, C

PY - 1989/3

Y1 - 1989/3

N2 - The pathogenesis of subchondral bone lesions and growth plate affection in hemophilic arthropathy was studied in puppies by means of repeated regional 99mTc-diphosphonate scintimetry and contact autoradiography. Unilateral hemarthrosis of the knee was induced by biweekly intraarticular injections of autologous blood for 12 weeks. Hemarthrosis caused an early (2 to 4 weeks) decrease in uptake of 99mTc-diphosphonate in the juxtaarticular growth plates (ratio 0.7) and a delayed (8 to 10 weeks) increase in epiphyseal uptake (ratio 1.5). In a recovery phase after hemarthrosis, growth plate uptake returned to normal, while the epiphyseal uptake remained elevated for 8 to 10 weeks. By contact autoradiography, the growth plate uptake was localized to the calcification layer at the metaphyseal aspect of the growth plates, while the epiphyseal uptake mainly was seen in the thin subchondral and subsynovial bone layer and around osteophytes. The changes in uptake of 99mTc-diphosphonate following hemarthrosis for 3 months were reversible and could be ascribed to the presence of synovial inflammation.

AB - The pathogenesis of subchondral bone lesions and growth plate affection in hemophilic arthropathy was studied in puppies by means of repeated regional 99mTc-diphosphonate scintimetry and contact autoradiography. Unilateral hemarthrosis of the knee was induced by biweekly intraarticular injections of autologous blood for 12 weeks. Hemarthrosis caused an early (2 to 4 weeks) decrease in uptake of 99mTc-diphosphonate in the juxtaarticular growth plates (ratio 0.7) and a delayed (8 to 10 weeks) increase in epiphyseal uptake (ratio 1.5). In a recovery phase after hemarthrosis, growth plate uptake returned to normal, while the epiphyseal uptake remained elevated for 8 to 10 weeks. By contact autoradiography, the growth plate uptake was localized to the calcification layer at the metaphyseal aspect of the growth plates, while the epiphyseal uptake mainly was seen in the thin subchondral and subsynovial bone layer and around osteophytes. The changes in uptake of 99mTc-diphosphonate following hemarthrosis for 3 months were reversible and could be ascribed to the presence of synovial inflammation.

KW - Animals

KW - Autoradiography

KW - Child

KW - Diphosphonates

KW - Disease Models, Animal

KW - Dogs

KW - Growth Plate/diagnostic imaging

KW - Hemarthrosis/diagnostic imaging

KW - Humans

KW - Knee Joint/blood supply

KW - Organometallic Compounds

KW - Organotechnetium Compounds

KW - Radiography

KW - Radionuclide Imaging

M3 - Journal article

C2 - 2710706

VL - 12

SP - 441

EP - 447

JO - Orthopedics

JF - Orthopedics

SN - 0147-7447

IS - 3

ER -

ID: 244329143