Standard
Exploratory study of ultraviolet B (UVB) radiation and age of onset of bipolar disorder. / Bauer, Michael; Glenn, Tasha; Achtyes, Eric D.; Alda, Martin; Agaoglu, Esen; Altınbaş, Kürsat; Andreassen, Ole A.; Angelopoulos, Elias; Ardau, Raffaella; Aydin, Memduha; Ayhan, Yavuz; Baethge, Christopher; Bauer, Rita; Baune, Bernhard T.; Balaban, Ceylan; Becerra-Palars, Claudia; Behere, Aniruddh P.; Behere, Prakash B.; Belete, Habte; Belete, Tilahun; Belizario, Gabriel Okawa; Bellivier, Frank; Belmaker, Robert H.; Benedetti, Francesco; Berk, Michael; Bersudsky, Yuly; Bicakci, Şule; Birabwa-Oketcho, Harriet; Bjella, Thomas D.; Brady, Conan; Cabrera, Jorge; Cappucciati, Marco; Castro, Angela Marianne Paredes; Chen, Wei Ling; Cheung, Eric Y.W.; Chiesa, Silvia; Crowe, Marie; Cuomo, Alessandro; Dallaspezia, Sara; Del Zompo, Maria; Desai, Pratikkumar; Dodd, Seetal; Etain, Bruno; Fagiolini, Andrea; Fellendorf, Frederike T.; Ferensztajn-Rochowiak, Ewa; Fiedorowicz, Jess G.; Fountoulakis, Kostas N.; Frye, Mark A.; Geoffroy, Pierre A.; Gitlin, Michael J.; Gonzalez-Pinto, Ana; Gottlieb, John F.; Grof, Paul; Haarman, Bartholomeus C.M.; Harima, Hirohiko; Hasse-Sousa, Mathias; Henry, Chantal; Hoffding, Lone; Houenou, Josselin; Imbesi, Massimiliano; Isometsä, Erkki T.; Ivkovic, Maja; Janno, Sven; Johnsen, Simon; Kapczinski, Flávio; Karakatsoulis, Gregory N.; Kardell, Mathias; Kessing, Lars Vedel; Kim, Seong Jae; König, Barbara; Kot, Timur L.; Koval, Michael; Kunz, Mauricio; Lafer, Beny; Landén, Mikael; Larsen, Erik R.; Lenger, Melanie; Licht, Rasmus W.; Lopez-Jaramillo, Carlos; MacKenzie, Alan; Madsen, Helle Østergaard; Madsen, Simone Alberte Kongstad A.; Mahadevan, Jayant; Mahardika, Agustine; Manchia, Mirko; Marsh, Wendy; Martinez-Cengotitabengoa, Monica; Martini, Julia; Martiny, Klaus; Mashima, Yuki; McLoughlin, Declan M.; Meesters, Ybe; Melle, Ingrid; Meza-Urzúa, Fátima; Mikolas, Pavol; Mok, Yee Ming; Monteith, Scott; Moorthy, Muthukumaran; Morken, Gunnar; Mosca, Enrica; Mozzhegorov, Anton A.; Munoz, Rodrigo; Mythri, Starlin V.; Nacef, Fethi; Nadella, Ravi K.; Nakanotani, Takako; Nielsen, René Ernst; O’Donovan, Claire; Omrani, Adel; Osher, Yamima; Ouali, Uta; Pantovic-Stefanovic, Maja; Pariwatcharakul, Pornjira; Petite, Joanne; Petzold, Johannes; Pfennig, Andrea; Ruiz, Yolanda Pica; Pinna, Marco; Pompili, Maurizio; Porter, Richard J.; Quiroz, Danilo; Rabelo-da-Ponte, Francisco Diego; Ramesar, Raj; Rasgon, Natalie; Ratta-apha, Woraphat; Ratzenhofer, Michaela; Redahan, Maria; Reddy, M. S.; Reif, Andreas; Reininghaus, Eva Z.; Richards, Jenny Gringer; Ritter, Philipp; Rybakowski, Janusz K.; Sathyaputri, Leela; Scippa, Angela M.; Simhandl, Christian; Smith, Daniel; Smith, José; Stackhouse, Paul W.; Stein, Dan J.; Stilwell, Kellen; Strejilevich, Sergio; Su, Kuan Pin; Subramaniam, Mythily; Sulaiman, Ahmad Hatim; Suominen, Kirsi; Tanra, Andi J.; Tatebayashi, Yoshitaka; Teh, Wen Lin; Tondo, Leonardo; Torrent, Carla; Tuinstra, Daniel; Uchida, Takahito; Vaaler, Arne E.; Vieta, Eduard; Viswanath, Biju; Yoldi-Negrete, Maria; Yalcinkaya, Oguz Kaan; Young, Allan H.; Zgueb, Yosra; Whybrow, Peter C.
I:
International Journal of Bipolar Disorders, Bind 11, Nr. 1, 22, 2023.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
Bauer, M, Glenn, T, Achtyes, ED, Alda, M, Agaoglu, E, Altınbaş, K, Andreassen, OA, Angelopoulos, E, Ardau, R, Aydin, M, Ayhan, Y, Baethge, C, Bauer, R, Baune, BT, Balaban, C, Becerra-Palars, C, Behere, AP, Behere, PB, Belete, H, Belete, T, Belizario, GO, Bellivier, F, Belmaker, RH, Benedetti, F, Berk, M, Bersudsky, Y, Bicakci, Ş, Birabwa-Oketcho, H, Bjella, TD, Brady, C, Cabrera, J, Cappucciati, M, Castro, AMP, Chen, WL, Cheung, EYW, Chiesa, S, Crowe, M, Cuomo, A, Dallaspezia, S, Del Zompo, M, Desai, P, Dodd, S, Etain, B, Fagiolini, A, Fellendorf, FT, Ferensztajn-Rochowiak, E, Fiedorowicz, JG, Fountoulakis, KN, Frye, MA, Geoffroy, PA, Gitlin, MJ, Gonzalez-Pinto, A, Gottlieb, JF, Grof, P, Haarman, BCM, Harima, H, Hasse-Sousa, M, Henry, C, Hoffding, L, Houenou, J, Imbesi, M, Isometsä, ET, Ivkovic, M, Janno, S, Johnsen, S, Kapczinski, F, Karakatsoulis, GN, Kardell, M
, Kessing, LV, Kim, SJ, König, B, Kot, TL, Koval, M, Kunz, M, Lafer, B, Landén, M, Larsen, ER, Lenger, M, Licht, RW, Lopez-Jaramillo, C, MacKenzie, A, Madsen, HØ, Madsen, SAKA, Mahadevan, J, Mahardika, A, Manchia, M, Marsh, W, Martinez-Cengotitabengoa, M, Martini, J
, Martiny, K, Mashima, Y, McLoughlin, DM, Meesters, Y, Melle, I, Meza-Urzúa, F, Mikolas, P, Mok, YM, Monteith, S, Moorthy, M, Morken, G, Mosca, E, Mozzhegorov, AA, Munoz, R, Mythri, SV, Nacef, F, Nadella, RK, Nakanotani, T, Nielsen, RE, O’Donovan, C, Omrani, A, Osher, Y, Ouali, U, Pantovic-Stefanovic, M, Pariwatcharakul, P, Petite, J, Petzold, J, Pfennig, A, Ruiz, YP, Pinna, M, Pompili, M, Porter, RJ, Quiroz, D, Rabelo-da-Ponte, FD, Ramesar, R, Rasgon, N, Ratta-apha, W, Ratzenhofer, M, Redahan, M, Reddy, MS, Reif, A, Reininghaus, EZ, Richards, JG, Ritter, P, Rybakowski, JK, Sathyaputri, L, Scippa, AM, Simhandl, C, Smith, D, Smith, J, Stackhouse, PW, Stein, DJ, Stilwell, K, Strejilevich, S, Su, KP, Subramaniam, M, Sulaiman, AH, Suominen, K, Tanra, AJ, Tatebayashi, Y, Teh, WL, Tondo, L, Torrent, C, Tuinstra, D, Uchida, T, Vaaler, AE, Vieta, E, Viswanath, B, Yoldi-Negrete, M, Yalcinkaya, OK, Young, AH, Zgueb, Y & Whybrow, PC 2023, '
Exploratory study of ultraviolet B (UVB) radiation and age of onset of bipolar disorder',
International Journal of Bipolar Disorders, bind 11, nr. 1, 22.
https://doi.org/10.1186/s40345-023-00303-wAPA
Bauer, M., Glenn, T., Achtyes, E. D., Alda, M., Agaoglu, E., Altınbaş, K., Andreassen, O. A., Angelopoulos, E., Ardau, R., Aydin, M., Ayhan, Y., Baethge, C., Bauer, R., Baune, B. T., Balaban, C., Becerra-Palars, C., Behere, A. P., Behere, P. B., Belete, H., ... Whybrow, P. C. (2023).
Exploratory study of ultraviolet B (UVB) radiation and age of onset of bipolar disorder.
International Journal of Bipolar Disorders,
11(1), [22].
https://doi.org/10.1186/s40345-023-00303-wVancouver
Bauer M, Glenn T, Achtyes ED, Alda M, Agaoglu E, Altınbaş K o.a.
Exploratory study of ultraviolet B (UVB) radiation and age of onset of bipolar disorder.
International Journal of Bipolar Disorders. 2023;11(1). 22.
https://doi.org/10.1186/s40345-023-00303-wAuthor
Bauer, Michael ; Glenn, Tasha ; Achtyes, Eric D. ; Alda, Martin ; Agaoglu, Esen ; Altınbaş, Kürsat ; Andreassen, Ole A. ; Angelopoulos, Elias ; Ardau, Raffaella ; Aydin, Memduha ; Ayhan, Yavuz ; Baethge, Christopher ; Bauer, Rita ; Baune, Bernhard T. ; Balaban, Ceylan ; Becerra-Palars, Claudia ; Behere, Aniruddh P. ; Behere, Prakash B. ; Belete, Habte ; Belete, Tilahun ; Belizario, Gabriel Okawa ; Bellivier, Frank ; Belmaker, Robert H. ; Benedetti, Francesco ; Berk, Michael ; Bersudsky, Yuly ; Bicakci, Şule ; Birabwa-Oketcho, Harriet ; Bjella, Thomas D. ; Brady, Conan ; Cabrera, Jorge ; Cappucciati, Marco ; Castro, Angela Marianne Paredes ; Chen, Wei Ling ; Cheung, Eric Y.W. ; Chiesa, Silvia ; Crowe, Marie ; Cuomo, Alessandro ; Dallaspezia, Sara ; Del Zompo, Maria ; Desai, Pratikkumar ; Dodd, Seetal ; Etain, Bruno ; Fagiolini, Andrea ; Fellendorf, Frederike T. ; Ferensztajn-Rochowiak, Ewa ; Fiedorowicz, Jess G. ; Fountoulakis, Kostas N. ; Frye, Mark A. ; Geoffroy, Pierre A. ; Gitlin, Michael J. ; Gonzalez-Pinto, Ana ; Gottlieb, John F. ; Grof, Paul ; Haarman, Bartholomeus C.M. ; Harima, Hirohiko ; Hasse-Sousa, Mathias ; Henry, Chantal ; Hoffding, Lone ; Houenou, Josselin ; Imbesi, Massimiliano ; Isometsä, Erkki T. ; Ivkovic, Maja ; Janno, Sven ; Johnsen, Simon ; Kapczinski, Flávio ; Karakatsoulis, Gregory N. ; Kardell, Mathias ; Kessing, Lars Vedel ; Kim, Seong Jae ; König, Barbara ; Kot, Timur L. ; Koval, Michael ; Kunz, Mauricio ; Lafer, Beny ; Landén, Mikael ; Larsen, Erik R. ; Lenger, Melanie ; Licht, Rasmus W. ; Lopez-Jaramillo, Carlos ; MacKenzie, Alan ; Madsen, Helle Østergaard ; Madsen, Simone Alberte Kongstad A. ; Mahadevan, Jayant ; Mahardika, Agustine ; Manchia, Mirko ; Marsh, Wendy ; Martinez-Cengotitabengoa, Monica ; Martini, Julia ; Martiny, Klaus ; Mashima, Yuki ; McLoughlin, Declan M. ; Meesters, Ybe ; Melle, Ingrid ; Meza-Urzúa, Fátima ; Mikolas, Pavol ; Mok, Yee Ming ; Monteith, Scott ; Moorthy, Muthukumaran ; Morken, Gunnar ; Mosca, Enrica ; Mozzhegorov, Anton A. ; Munoz, Rodrigo ; Mythri, Starlin V. ; Nacef, Fethi ; Nadella, Ravi K. ; Nakanotani, Takako ; Nielsen, René Ernst ; O’Donovan, Claire ; Omrani, Adel ; Osher, Yamima ; Ouali, Uta ; Pantovic-Stefanovic, Maja ; Pariwatcharakul, Pornjira ; Petite, Joanne ; Petzold, Johannes ; Pfennig, Andrea ; Ruiz, Yolanda Pica ; Pinna, Marco ; Pompili, Maurizio ; Porter, Richard J. ; Quiroz, Danilo ; Rabelo-da-Ponte, Francisco Diego ; Ramesar, Raj ; Rasgon, Natalie ; Ratta-apha, Woraphat ; Ratzenhofer, Michaela ; Redahan, Maria ; Reddy, M. S. ; Reif, Andreas ; Reininghaus, Eva Z. ; Richards, Jenny Gringer ; Ritter, Philipp ; Rybakowski, Janusz K. ; Sathyaputri, Leela ; Scippa, Angela M. ; Simhandl, Christian ; Smith, Daniel ; Smith, José ; Stackhouse, Paul W. ; Stein, Dan J. ; Stilwell, Kellen ; Strejilevich, Sergio ; Su, Kuan Pin ; Subramaniam, Mythily ; Sulaiman, Ahmad Hatim ; Suominen, Kirsi ; Tanra, Andi J. ; Tatebayashi, Yoshitaka ; Teh, Wen Lin ; Tondo, Leonardo ; Torrent, Carla ; Tuinstra, Daniel ; Uchida, Takahito ; Vaaler, Arne E. ; Vieta, Eduard ; Viswanath, Biju ; Yoldi-Negrete, Maria ; Yalcinkaya, Oguz Kaan ; Young, Allan H. ; Zgueb, Yosra ; Whybrow, Peter C. / Exploratory study of ultraviolet B (UVB) radiation and age of onset of bipolar disorder. I: International Journal of Bipolar Disorders. 2023 ; Bind 11, Nr. 1.
Bibtex
@article{96cfe1a4bbd745c895b07d3206dae84c,
title = "Exploratory study of ultraviolet B (UVB) radiation and age of onset of bipolar disorder",
abstract = "Background: Sunlight contains ultraviolet B (UVB) radiation that triggers the production of vitamin D by skin. Vitamin D has widespread effects on brain function in both developing and adult brains. However, many people live at latitudes (about > 40 N or S) that do not receive enough UVB in winter to produce vitamin D. This exploratory study investigated the association between the age of onset of bipolar I disorder and the threshold for UVB sufficient for vitamin D production in a large global sample. Methods: Data for 6972 patients with bipolar I disorder were obtained at 75 collection sites in 41 countries in both hemispheres. The best model to assess the relation between the threshold for UVB sufficient for vitamin D production and age of onset included 1 or more months below the threshold, family history of mood disorders, and birth cohort. All coefficients estimated at P ≤ 0.001. Results: The 6972 patients had an onset in 582 locations in 70 countries, with a mean age of onset of 25.6 years. Of the onset locations, 34.0% had at least 1 month below the threshold for UVB sufficient for vitamin D production. The age of onset at locations with 1 or more months of less than or equal to the threshold for UVB was 1.66 years younger. Conclusion: UVB and vitamin D may have an important influence on the development of bipolar disorder. Study limitations included a lack of data on patient vitamin D levels, lifestyles, or supplement use. More study of the impacts of UVB and vitamin D in bipolar disorder is needed to evaluate this supposition.",
author = "Michael Bauer and Tasha Glenn and Achtyes, {Eric D.} and Martin Alda and Esen Agaoglu and K{\"u}rsat Altınba{\c s} and Andreassen, {Ole A.} and Elias Angelopoulos and Raffaella Ardau and Memduha Aydin and Yavuz Ayhan and Christopher Baethge and Rita Bauer and Baune, {Bernhard T.} and Ceylan Balaban and Claudia Becerra-Palars and Behere, {Aniruddh P.} and Behere, {Prakash B.} and Habte Belete and Tilahun Belete and Belizario, {Gabriel Okawa} and Frank Bellivier and Belmaker, {Robert H.} and Francesco Benedetti and Michael Berk and Yuly Bersudsky and {\c S}ule Bicakci and Harriet Birabwa-Oketcho and Bjella, {Thomas D.} and Conan Brady and Jorge Cabrera and Marco Cappucciati and Castro, {Angela Marianne Paredes} and Chen, {Wei Ling} and Cheung, {Eric Y.W.} and Silvia Chiesa and Marie Crowe and Alessandro Cuomo and Sara Dallaspezia and {Del Zompo}, Maria and Pratikkumar Desai and Seetal Dodd and Bruno Etain and Andrea Fagiolini and Fellendorf, {Frederike T.} and Ewa Ferensztajn-Rochowiak and Fiedorowicz, {Jess G.} and Fountoulakis, {Kostas N.} and Frye, {Mark A.} and Geoffroy, {Pierre A.} and Gitlin, {Michael J.} and Ana Gonzalez-Pinto and Gottlieb, {John F.} and Paul Grof and Haarman, {Bartholomeus C.M.} and Hirohiko Harima and Mathias Hasse-Sousa and Chantal Henry and Lone Hoffding and Josselin Houenou and Massimiliano Imbesi and Isomets{\"a}, {Erkki T.} and Maja Ivkovic and Sven Janno and Simon Johnsen and Fl{\'a}vio Kapczinski and Karakatsoulis, {Gregory N.} and Mathias Kardell and Kessing, {Lars Vedel} and Kim, {Seong Jae} and Barbara K{\"o}nig and Kot, {Timur L.} and Michael Koval and Mauricio Kunz and Beny Lafer and Mikael Land{\'e}n and Larsen, {Erik R.} and Melanie Lenger and Licht, {Rasmus W.} and Carlos Lopez-Jaramillo and Alan MacKenzie and Madsen, {Helle {\O}stergaard} and Madsen, {Simone Alberte Kongstad A.} and Jayant Mahadevan and Agustine Mahardika and Mirko Manchia and Wendy Marsh and Monica Martinez-Cengotitabengoa and Julia Martini and Klaus Martiny and Yuki Mashima and McLoughlin, {Declan M.} and Ybe Meesters and Ingrid Melle and F{\'a}tima Meza-Urz{\'u}a and Pavol Mikolas and Mok, {Yee Ming} and Scott Monteith and Muthukumaran Moorthy and Gunnar Morken and Enrica Mosca and Mozzhegorov, {Anton A.} and Rodrigo Munoz and Mythri, {Starlin V.} and Fethi Nacef and Nadella, {Ravi K.} and Takako Nakanotani and Nielsen, {Ren{\'e} Ernst} and Claire O{\textquoteright}Donovan and Adel Omrani and Yamima Osher and Uta Ouali and Maja Pantovic-Stefanovic and Pornjira Pariwatcharakul and Joanne Petite and Johannes Petzold and Andrea Pfennig and Ruiz, {Yolanda Pica} and Marco Pinna and Maurizio Pompili and Porter, {Richard J.} and Danilo Quiroz and Rabelo-da-Ponte, {Francisco Diego} and Raj Ramesar and Natalie Rasgon and Woraphat Ratta-apha and Michaela Ratzenhofer and Maria Redahan and Reddy, {M. S.} and Andreas Reif and Reininghaus, {Eva Z.} and Richards, {Jenny Gringer} and Philipp Ritter and Rybakowski, {Janusz K.} and Leela Sathyaputri and Scippa, {Angela M.} and Christian Simhandl and Daniel Smith and Jos{\'e} Smith and Stackhouse, {Paul W.} and Stein, {Dan J.} and Kellen Stilwell and Sergio Strejilevich and Su, {Kuan Pin} and Mythily Subramaniam and Sulaiman, {Ahmad Hatim} and Kirsi Suominen and Tanra, {Andi J.} and Yoshitaka Tatebayashi and Teh, {Wen Lin} and Leonardo Tondo and Carla Torrent and Daniel Tuinstra and Takahito Uchida and Vaaler, {Arne E.} and Eduard Vieta and Biju Viswanath and Maria Yoldi-Negrete and Yalcinkaya, {Oguz Kaan} and Young, {Allan H.} and Yosra Zgueb and Whybrow, {Peter C.}",
note = "Publisher Copyright: {\textcopyright} 2023, The Author(s).",
year = "2023",
doi = "10.1186/s40345-023-00303-w",
language = "English",
volume = "11",
journal = "International Journal of Bipolar Disorders",
issn = "2194-7511",
publisher = "SpringerOpen",
number = "1",
}
RIS
TY - JOUR
T1 - Exploratory study of ultraviolet B (UVB) radiation and age of onset of bipolar disorder
AU - Bauer, Michael
AU - Glenn, Tasha
AU - Achtyes, Eric D.
AU - Alda, Martin
AU - Agaoglu, Esen
AU - Altınbaş, Kürsat
AU - Andreassen, Ole A.
AU - Angelopoulos, Elias
AU - Ardau, Raffaella
AU - Aydin, Memduha
AU - Ayhan, Yavuz
AU - Baethge, Christopher
AU - Bauer, Rita
AU - Baune, Bernhard T.
AU - Balaban, Ceylan
AU - Becerra-Palars, Claudia
AU - Behere, Aniruddh P.
AU - Behere, Prakash B.
AU - Belete, Habte
AU - Belete, Tilahun
AU - Belizario, Gabriel Okawa
AU - Bellivier, Frank
AU - Belmaker, Robert H.
AU - Benedetti, Francesco
AU - Berk, Michael
AU - Bersudsky, Yuly
AU - Bicakci, Şule
AU - Birabwa-Oketcho, Harriet
AU - Bjella, Thomas D.
AU - Brady, Conan
AU - Cabrera, Jorge
AU - Cappucciati, Marco
AU - Castro, Angela Marianne Paredes
AU - Chen, Wei Ling
AU - Cheung, Eric Y.W.
AU - Chiesa, Silvia
AU - Crowe, Marie
AU - Cuomo, Alessandro
AU - Dallaspezia, Sara
AU - Del Zompo, Maria
AU - Desai, Pratikkumar
AU - Dodd, Seetal
AU - Etain, Bruno
AU - Fagiolini, Andrea
AU - Fellendorf, Frederike T.
AU - Ferensztajn-Rochowiak, Ewa
AU - Fiedorowicz, Jess G.
AU - Fountoulakis, Kostas N.
AU - Frye, Mark A.
AU - Geoffroy, Pierre A.
AU - Gitlin, Michael J.
AU - Gonzalez-Pinto, Ana
AU - Gottlieb, John F.
AU - Grof, Paul
AU - Haarman, Bartholomeus C.M.
AU - Harima, Hirohiko
AU - Hasse-Sousa, Mathias
AU - Henry, Chantal
AU - Hoffding, Lone
AU - Houenou, Josselin
AU - Imbesi, Massimiliano
AU - Isometsä, Erkki T.
AU - Ivkovic, Maja
AU - Janno, Sven
AU - Johnsen, Simon
AU - Kapczinski, Flávio
AU - Karakatsoulis, Gregory N.
AU - Kardell, Mathias
AU - Kessing, Lars Vedel
AU - Kim, Seong Jae
AU - König, Barbara
AU - Kot, Timur L.
AU - Koval, Michael
AU - Kunz, Mauricio
AU - Lafer, Beny
AU - Landén, Mikael
AU - Larsen, Erik R.
AU - Lenger, Melanie
AU - Licht, Rasmus W.
AU - Lopez-Jaramillo, Carlos
AU - MacKenzie, Alan
AU - Madsen, Helle Østergaard
AU - Madsen, Simone Alberte Kongstad A.
AU - Mahadevan, Jayant
AU - Mahardika, Agustine
AU - Manchia, Mirko
AU - Marsh, Wendy
AU - Martinez-Cengotitabengoa, Monica
AU - Martini, Julia
AU - Martiny, Klaus
AU - Mashima, Yuki
AU - McLoughlin, Declan M.
AU - Meesters, Ybe
AU - Melle, Ingrid
AU - Meza-Urzúa, Fátima
AU - Mikolas, Pavol
AU - Mok, Yee Ming
AU - Monteith, Scott
AU - Moorthy, Muthukumaran
AU - Morken, Gunnar
AU - Mosca, Enrica
AU - Mozzhegorov, Anton A.
AU - Munoz, Rodrigo
AU - Mythri, Starlin V.
AU - Nacef, Fethi
AU - Nadella, Ravi K.
AU - Nakanotani, Takako
AU - Nielsen, René Ernst
AU - O’Donovan, Claire
AU - Omrani, Adel
AU - Osher, Yamima
AU - Ouali, Uta
AU - Pantovic-Stefanovic, Maja
AU - Pariwatcharakul, Pornjira
AU - Petite, Joanne
AU - Petzold, Johannes
AU - Pfennig, Andrea
AU - Ruiz, Yolanda Pica
AU - Pinna, Marco
AU - Pompili, Maurizio
AU - Porter, Richard J.
AU - Quiroz, Danilo
AU - Rabelo-da-Ponte, Francisco Diego
AU - Ramesar, Raj
AU - Rasgon, Natalie
AU - Ratta-apha, Woraphat
AU - Ratzenhofer, Michaela
AU - Redahan, Maria
AU - Reddy, M. S.
AU - Reif, Andreas
AU - Reininghaus, Eva Z.
AU - Richards, Jenny Gringer
AU - Ritter, Philipp
AU - Rybakowski, Janusz K.
AU - Sathyaputri, Leela
AU - Scippa, Angela M.
AU - Simhandl, Christian
AU - Smith, Daniel
AU - Smith, José
AU - Stackhouse, Paul W.
AU - Stein, Dan J.
AU - Stilwell, Kellen
AU - Strejilevich, Sergio
AU - Su, Kuan Pin
AU - Subramaniam, Mythily
AU - Sulaiman, Ahmad Hatim
AU - Suominen, Kirsi
AU - Tanra, Andi J.
AU - Tatebayashi, Yoshitaka
AU - Teh, Wen Lin
AU - Tondo, Leonardo
AU - Torrent, Carla
AU - Tuinstra, Daniel
AU - Uchida, Takahito
AU - Vaaler, Arne E.
AU - Vieta, Eduard
AU - Viswanath, Biju
AU - Yoldi-Negrete, Maria
AU - Yalcinkaya, Oguz Kaan
AU - Young, Allan H.
AU - Zgueb, Yosra
AU - Whybrow, Peter C.
N1 - Publisher Copyright:
© 2023, The Author(s).
PY - 2023
Y1 - 2023
N2 - Background: Sunlight contains ultraviolet B (UVB) radiation that triggers the production of vitamin D by skin. Vitamin D has widespread effects on brain function in both developing and adult brains. However, many people live at latitudes (about > 40 N or S) that do not receive enough UVB in winter to produce vitamin D. This exploratory study investigated the association between the age of onset of bipolar I disorder and the threshold for UVB sufficient for vitamin D production in a large global sample. Methods: Data for 6972 patients with bipolar I disorder were obtained at 75 collection sites in 41 countries in both hemispheres. The best model to assess the relation between the threshold for UVB sufficient for vitamin D production and age of onset included 1 or more months below the threshold, family history of mood disorders, and birth cohort. All coefficients estimated at P ≤ 0.001. Results: The 6972 patients had an onset in 582 locations in 70 countries, with a mean age of onset of 25.6 years. Of the onset locations, 34.0% had at least 1 month below the threshold for UVB sufficient for vitamin D production. The age of onset at locations with 1 or more months of less than or equal to the threshold for UVB was 1.66 years younger. Conclusion: UVB and vitamin D may have an important influence on the development of bipolar disorder. Study limitations included a lack of data on patient vitamin D levels, lifestyles, or supplement use. More study of the impacts of UVB and vitamin D in bipolar disorder is needed to evaluate this supposition.
AB - Background: Sunlight contains ultraviolet B (UVB) radiation that triggers the production of vitamin D by skin. Vitamin D has widespread effects on brain function in both developing and adult brains. However, many people live at latitudes (about > 40 N or S) that do not receive enough UVB in winter to produce vitamin D. This exploratory study investigated the association between the age of onset of bipolar I disorder and the threshold for UVB sufficient for vitamin D production in a large global sample. Methods: Data for 6972 patients with bipolar I disorder were obtained at 75 collection sites in 41 countries in both hemispheres. The best model to assess the relation between the threshold for UVB sufficient for vitamin D production and age of onset included 1 or more months below the threshold, family history of mood disorders, and birth cohort. All coefficients estimated at P ≤ 0.001. Results: The 6972 patients had an onset in 582 locations in 70 countries, with a mean age of onset of 25.6 years. Of the onset locations, 34.0% had at least 1 month below the threshold for UVB sufficient for vitamin D production. The age of onset at locations with 1 or more months of less than or equal to the threshold for UVB was 1.66 years younger. Conclusion: UVB and vitamin D may have an important influence on the development of bipolar disorder. Study limitations included a lack of data on patient vitamin D levels, lifestyles, or supplement use. More study of the impacts of UVB and vitamin D in bipolar disorder is needed to evaluate this supposition.
UR - http://www.scopus.com/inward/record.url?scp=85162906391&partnerID=8YFLogxK
U2 - 10.1186/s40345-023-00303-w
DO - 10.1186/s40345-023-00303-w
M3 - Journal article
C2 - 37347392
AN - SCOPUS:85162906391
VL - 11
JO - International Journal of Bipolar Disorders
JF - International Journal of Bipolar Disorders
SN - 2194-7511
IS - 1
M1 - 22
ER -
